Cancer

Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors  BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 18/August/2017, 11.03 pm
Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors  BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 18/August/2017, 11.03 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Molecular therapy for metastatic prostate cancer: Ivermectin (Brand name: Heartguard/Mectizen) inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 17/August/2017, 10.15 pm
Molecular therapy for metastatic prostate cancer: Ivermectin (Brand name: Heartguard/Mectizen) inhibits the expression of CDC42, CDC42EP3, RAC1 and ARPC5, and GAS6, suppresses the expression of stem cell molecules CD44 and EZH2, promotes epithelial phenotype, suppresses tumorigenesis, migration, invasion, stem cell regeneration and metastasis via up regulation of its target gene, 17/August/2017, 10.15 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center, Science Park, Texas 78957, USA shows that “MicroRNA-141 suppresses…

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Natural product-derived therapy for gynecologic cancers: Shikonin, one of the main components of herb Zicao, inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 17/August/2017, 12.57 am
Natural product-derived therapy for gynecologic cancers: Shikonin, one of the main components of herb Zicao, inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers via up-regulation of its target gene, 17/August/2017, 12.57 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania 19104, USA shows that “ARID1A-mutated ovarian cancers depend on HDAC6 activity” This study…

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Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors TAp63 and TPM1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 17/August/2017, 12.51 am
Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors TAp63 and TPM1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 17/August/2017, 12.51 am 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors TIMP3 and CCM3/KRIT1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 15/August/2017, 11.31 pm
Molecular therapy for Metastatic cancers: Ivermectin, the anthelmintic drug, increases the expression of metastasis suppressors TIMP3 and CCM3/KRIT1, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 15/August/2017, 11.31 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Molecular therapy for glioblastoma: Magnolol, isolated from bark of the Houpu magnolia, inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 13/August/2017, 11.27 pm
Molecular therapy for glioblastoma: Magnolol, isolated from bark of the Houpu magnolia, inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 13/August/2017, 11.27 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors represent in vivo cancer…

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