Cancer

September 6, 2017

Natural product-derived CDK4/6 pathway blockade enhances the efficacy of Cancer immunotherapy: A pharmacological mixture encompassing Rosuvastatin, Tubastatin, Trichodermin, 17-DMAG, Cisplatin, Linalool  (RTTDCL)  inhibits the expression of cell cycle protein CDK4/CDK6, increases levels of T-III IFNs, inhibits the proliferation of Treg cells, decreases DNMT1 expression, inhibits the expression of a number of immune evasion molecules, increases antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target genes, 7/September/2017,12.13 am

Introduction:What they say: A recent study from Division of Molecular Oncology & Immunology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands has identified […]
September 6, 2017

Molecular therapy for Metastatic cancers: Myrtenal, isolated  from Taxus, increases the expression of context-dependent tumor suppressors  Sox2 and IL1-β, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 6/September/2017, 11.42 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
September 5, 2017

Natural product-derived therapy for Metastatic human tumors:  A pharmaceutical mixture encompassing Nimbolide and Curcumin  decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via up regulation of its target gene, 05/September/2017, 11.58 pm

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]
September 5, 2017

Molecular therapy for Metastatic cancers: Myrtenal, isolated  from Taxus, increases the expression of DNA repair protein hMSH2 and the tumor suppressor protein CADM1 , inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 5/September/2017, 11.43 pm

Teacher’s day special ********* We wish everyone a happy Teacher’s day. On this special occasion, we are happy to announce that ideas posted today (05/September/2017) will be available to […]