Diabetes

December 9, 2018

Molecular therapy for TIIDM and obesity-associated metabolic deficits: Memantine (brand name: Axura, Ebixa, Namenda),  an anti-alzheimer’s drug,  increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 9/December/2018, 11.58 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]
December 9, 2018

Repurposing the anti-psychotic medication into an anti-diabetic medication: Amisulpride (brand name: Solian), an antipsychotic medication used to treat schizophrenia, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 9/December/2018, 11.36 pm

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, the University of Alabama at […]
December 7, 2018

A probiotic way to say no to weight gain and Diabetes: Probiotic-based therapy for body weight control, energy homeostasis and TIIDM: Probiotic Bifidobacterium pseudocatenulatum  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 7/December/2018, 10.22 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
November 23, 2018

Hot water immersion therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Hot water immersion (at 39C for 1 hour) increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 23/November/2018, 10.48 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]