Diabetes

March 3, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Lactulose (Brand names: Cholac, Generlac, Consulose, Duphalac), a non-absorbable sugar that aids in the treatment of constipation and hepatic encephalopathy,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2017, 9.10 am

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
March 3, 2018

Polyamine-based therapy for diabetes (TIDM): Spermidine, a natural polyamine, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2018, 8.47 am

Introduction: What they say   A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]
March 2, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: Spermidine, an endogenous polyamine, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/March/2018, 7.17 am

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
February 28, 2018

Molecular therapy for TIIDM and Metabolic defects: Syringic acid increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 28/November/2017, 11.43 pm

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma ideas posted […]