Diabetes

Combinatorial therapy for body weight control, energy homeostasis and TIIDM: A therapeutic mix encompassing Arctigenin and AICAR decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 28/July/2017, 12.05 am
Combinatorial therapy for body weight control, energy homeostasis and TIIDM: A therapeutic mix encompassing Arctigenin and AICAR decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 28/July/2017, 12.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.” This research paper…

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Folate-based regenerative therapy for reversing diabetes: Folic acid increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 25/July/2017, 11.00 am
Folate-based regenerative therapy for reversing diabetes: Folic acid increases the expression of Sox17, Sox2, Pdx-1, and Ngn3, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 25/July/2017, 11.00 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, California, USA; and Koch Institute at MIT, 500 Main Street,…

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Hydrogen Sulfide (H2S)-based therapy for TIIDM and obesity-associated metabolic deficits: Hydrogen Sulfide (H2S) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 23/July/2017, 11.52 pm
Hydrogen Sulfide (H2S)-based therapy for TIIDM and obesity-associated metabolic deficits: Hydrogen Sulfide (H2S) increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 23/July/2017, 11.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite…

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Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Artesunate, a derivative of artemisinin isolated from Artemesia annal l, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 23/July/2017, 11.41 pm
Natural product derived-therapy for Regenerating the lost pancreatic β-cells in Diabetic patients:  Artesunate, a derivative of artemisinin isolated from Artemesia annal l, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 23/July/2017, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Natural product-based therapy for glucose homeostasis and TIIDM: Artesunate, a derivative of artemisinin isolated from Artemesia Annua L, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of  Sox4 and its target gene Amysin,  23/July/2017, 11.33 pm
Natural product-based therapy for glucose homeostasis and TIIDM: Artesunate, a derivative of artemisinin isolated from Artemesia Annua L, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia via down regulation of  Sox4 and its target gene Amysin,  23/July/2017, 11.33 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say Nobel laureate in Physiology/Medicine (1975) Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014 issue of the Journal “Journal of Experimental…

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Natural product-derived therapy for therapy-resistant cancers: γ-bisabolene, one of the components of Cardamom, inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 22/July/2017, 11.59 pm
Natural product-derived therapy for therapy-resistant cancers: γ-bisabolene, one of the components of Cardamom, inhibits the expression of phospholipid glutathione peroxidase (GPX4), inhibits GPX4 signaling network and lipid peroxidase pathway, suppresses EMT protein ZEB1, increases sensitivity to anticancer therapy and prolongs survival via up regulation of its target gene, 22/July/2017, 11.59 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Broad Institute, Cambridge, Massachusetts, USA, Howard Hughes Medical Institute, Chevy Chase, Maryland and Department of Chemistry and Chemical Biology, Harvard University, Oxford St., Cambridge, Massachusetts, USA shows…

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