Heart attack

December 3, 2017

Molecular therapy for Myocardial Infarction: Cilostazol, a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 3/December/2017, 9.35 pm

Molecular therapy for Myocardial Infarction: Cilostazol, a phosphodiesterase inhibitor used in the treatment of peripheral vascular disease, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up regulation of PNUTS, 3/December/2017, 9.35 pm https://genomediscovery.org/wp-content/uploads/2017/12/Cilotazole-may-protect-against-cardiac-ageing-and-myocardial-infarction-through-up-regulation-of-PNUTS1.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/12/Cilotazole-may-protect-against-cardiac-ageing-and-myocardial-infarction-through-up-regulation-of-PNUTS1.jpg December 3, 2017 December 3, 2017

What they say: A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March 2013 issue of Nature, by Prof Dimmler, Boon, and others. What we…

December 2, 2017

Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Aripiprazole and Cilostazol increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 2/December/2017, 8.39 am

Molecular therapy for heart regeneration and repair: A therapeutic mix encompassing Aripiprazole and Cilostazol increases Agrin expression, activates Yap and ERK-mediated signaling, replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 2/December/2017, 8.39 am https://genomediscovery.org/wp-content/uploads/2017/12/A-pharmaceutical-mixture-encompassing-Cilostazol-and-Aripiprazole-may-prevent-myocordial-infarction.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/12/A-pharmaceutical-mixture-encompassing-Cilostazol-and-Aripiprazole-may-prevent-myocordial-infarction.jpg December 2, 2017 December 3, 2017

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

November 28, 2017

Natural product-derived therapy for attenuating associated with Myocardial infarction: Harmine, found in Peganum harmala, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 28/November/2017, 11.48 pm

Natural product-derived therapy for attenuating associated with Myocardial infarction: Harmine, found in Peganum harmala, decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 28/November/2017, 11.48 pm https://genomediscovery.org/wp-content/uploads/2017/11/Harmine-may-attenuate-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-GM-CSF-and-other-inflammatory-mediators2.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/11/Harmine-may-attenuate-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-GM-CSF-and-other-inflammatory-mediators2.jpg November 28, 2017 November 28, 2017

Introduction: What they say: A recent study from Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; and Center for Systems Biology, Massachusetts General Hospital…

November 25, 2017

Natural product-derived therapy for Myocardial Infarction: Hypaphorine, isolated from Caragana korshinskii Kom, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 25/November/2017, 3.55 pm

Natural product-derived therapy for Myocardial Infarction: Hypaphorine, isolated from Caragana korshinskii Kom, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction via up-regulation of PNUTS, 25/November/2017, 3.55 pm https://genomediscovery.org/wp-content/uploads/2017/11/Hypaphorine-may-protect-against-cardiac-ageing-and-myocardial-infarction-through-up-regulation-of-PNUTS.jpg2_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/11/Hypaphorine-may-protect-against-cardiac-ageing-and-myocardial-infarction-through-up-regulation-of-PNUTS.jpg2_.jpg November 25, 2017 November 25, 2017

November 20, 2017

Natural product-derived therapy for attenuating pathogenesis associated with Myocardial infarction: A pharmaceutical mix encompassing Bixin and Norbixin decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 20/November/2017, 8.46 am

Natural product-derived therapy for attenuating pathogenesis associated with Myocardial infarction: A pharmaceutical mix encompassing Bixin and Norbixin decreases GM-CSF (Granulocyte-macrophage colony-stimulating factor) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits left ventricular rupture, and promotes heart healing via up regulation of its target gene, 20/November/2017, 8.46 am https://genomediscovery.org/wp-content/uploads/2017/11/Bixin-and-NorBixin-may-attenuate-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-GM-CSF-and-other-inflammatory-mediators2.jpg3_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/11/Bixin-and-NorBixin-may-attenuate-pathogenesis-associated-with-myocardial-infarction-through-down-regulation-of-GM-CSF-and-other-inflammatory-mediators2.jpg3_.jpg November 20, 2017 November 20, 2017

November 18, 2017

Combinatorial therapy for Cardiac rejuvenation, diabetic-associated complications and Hypertension: A therapeutic mix encompassing Aspirin and Fidarestat (AF) suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and senescence, attenuates diabetic nephropathy, insulin resistance and hypertension and extends life span via up regulation of its target gene, 18/November/2017, 8.03 am

Combinatorial therapy for Cardiac rejuvenation, diabetic-associated complications and Hypertension: A therapeutic mix encompassing Aspirin and Fidarestat (AF) suppresses tumor suppressor INK4a/p16 expression, promotes cardiac repair, delays cardiac ageing and senescence, attenuates diabetic nephropathy, insulin resistance and hypertension and extends life span via up regulation of its target gene, 18/November/2017, 8.03 am https://genomediscovery.org/wp-content/uploads/2017/11/Asprin-and-Fidarestat-AF-promote-Cardiomyocyte-CM-dedifferentiation-and-proliferation-inhibits-Cardiac-senescence-cardiomyopathy-Diabetic-nephropathy-1.jpg2_.jpg3_.jpg4_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2017/11/Asprin-and-Fidarestat-AF-promote-Cardiomyocyte-CM-dedifferentiation-and-proliferation-inhibits-Cardiac-senescence-cardiomyopathy-Diabetic-nephropathy-1.jpg2_.jpg3_.jpg4_.jpg November 18, 2017 November 18, 2017

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Combinatorial therapy for Cardiac rejuvenation, diabetic-associated complications and Hypertension: A therapeutic mix encompassing Aspirin and Fidarestat (AF) suppresses tumor suppressor…

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