Molecular therapy for pulmonary arterial hypertension (PAH): Exemestane (brand name Aromasin), a drug used to treat breast cancer, inhibits the development of pulmonary arterial hypertension via down-regulation of its target gene Notch3, 26/August/2018, 11.03 pm
What they say: A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November 2009 issue of the journal “Nature Medicine“[the number 1 journal in General Medicine with an I.F of 28.054], by Prof. Thistlethwaite PA, Li X and others. What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist […]
Repurposing the H.Pylori vaccine CTB-UE into a pulmonary arterial hypertension (PAH) vaccine: CTB-UE, a Helicobacter Pyroli vaccine, inhibits the development of pulmonary arterial hypertension via down-regulation of its target gene Notch3, 20/July/2018, 1.22 pm
What they say: A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November 2009 issue of the journal “Nature Medicine“[the number 1 journal in General Medicine with an I.F of 28.054], by Prof. Thistlethwaite PA, Li X and others. What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist […]
Flavonoid your way to decrease blood pressure/sugar and extend lifespan: Quercetin-based Lifespan and healthspan extension therapy: Quercetin, a flavonoid isolated from elder berries and onions, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 18/July/2018, 7.47 am
Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1) gene results in marked prolongation of mammalian lifespan. From research findings to therapeutic opportunity: This study suggests, for the first time, that Quercetin, by increasing the expression of […]
Bacillus Calmette Guerin (BCG) vaccine-based therapy for pulmonary arterial hypertension: Repurposing tuberculosis vaccine into a pulmonary arterial hypertensive vaccine: BCG, a tuberculosis vaccine, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 1/July/2018, 11.36 pm
What they say: A study from the University of California, La Jolla, California, USA shows that “Notch3 signaling promotes the development of pulmonary arterial hypertension.” This study was published, in the 15 November 2009 issue of the journal “Nature Medicine”[the number 1 journal in General Medicine with an I.F of 28.054], by Prof. Thistlethwaite PA, Li X and others. What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, Director-cum-chief Scientist […]
Bonding your way to decrease blood pressure/sugar and extend lifespan: Oxytocin-based Lifespan and healthspan extension therapy: Oxytocin, a peptide hormone and neuropeptide known to play a role in empathy, generosity, child birth and so on, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 13/April/2018, 7.09 am
Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown that disruption of AT1R (AGTR1) gene results in marked prolongation of mammalian lifespan. From research findings to therapeutic opportunity: This study suggests, for the first time, that oxytocin, by increasing the expression of […]
Molecular therapy for pulmonary arterial hypertension: Spermidine, an endogenous polyamine, inhibits the development of pulmonary arterial hypertension via down regulation of its target gene Notch3, 28/February/2018, 10.56 pm
National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma ideas posted today (28/February/2018) will be available to the use of Scientists/Professors/Teachers/Physicians/Researchers for free. So, there will be no terms and conditions for the ideas posted today. Each idea posted will be served first come, […]
