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Ideas

April 20, 2018

Natural product-derived therapy for cardiomyocyte proliferation and heart regeneration: A pharmaceutical mixture encompassing Naringenin, Geniposide and Fortunellin(NGF) decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 20/April/2018, 3.21 pm

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
April 20, 2018

Olive oil-based therapy for Deafness: A therapeutic mix encompassing Hydroxytyrosol, Cholecalciferol, Ajoene and DIM (HTCAD) increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 20/April/2018, 2.50 pm

  What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Olive oil-based therapy for Deafness: A therapeutic mix encompassing Hydroxytyrosol, Cholecalciferol, Ajoene and DIM (HTCAD) increases […]
April 20, 2018

Turning on the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, increases the expression of tumor suppressors genes, such as BigH3, TIPE2, PTEN, PDCD4, INK4a, BTG2, TA-p73/p63, TPM1, TIMP3, CCM1/KRIT1 and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/April/2017, 2.42 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
April 20, 2018

Bonding your way to live longer: Oxytocin-based anti-ageing and Lifespan extension therapy: Oxytocin (also known as compassion/goodness/bonding hormone), a peptide hormone and neuropeptide known to play a role in empathy, generosity, childbirth and so on, increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 20/April/2018, 12.38 pm

Introduction: What they say  A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
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