Ideas

June 10, 2019

A coconut way to say no to weight gain and Diabetes: Coconut oil-derived compound Lauric acid plays a significant role in body weight control, energy homeostasis and TIIDM: Lauric acid (LA-C12) or Dodecanoic acid (DA), one of the main components (48-52%) of coconut oil,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/June/2019, 11.14 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
June 9, 2019

A long myth that how coconut oil lowers cholesterol and triglyceride and increases HDL levels is explained: Lauric acid-based therapy for Non-alcoholic fatty liver disease (NAFLD):Lauric acid (C12) or Dodecanoic acid, one of the main components of  coconut oil, promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down-regulation of its target gene, 9/June/2018, 11.17 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
June 9, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as TIMP3, PTPN14, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 09/June/2019, 6.23 pm

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research […]
June 8, 2019

Curing autoimmune diabetes  (TIDM) with commonly available blood pressure drug Carvedilol:  Carvedilol-based therapy for autoimmune diabetes: Carvedilol (brand name: Coreg and others),  a non-selective beta blocker used to treat high blood pressure and congestive heart failure, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 8/June/2019, 11.22 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
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