Ideas

April 18, 2018

Published by admin_auro at April 18, 2018

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Androsterone-based therapy for blood sugar disease (autoimmune diabetes (TIDM)): Dehydroepiandrosterone (DHEA) and its metabolite HE3286 (17α-ethynyl-5-androstene-3β,7β,17β-triol) increase PD-L1 expression, augment Tregs function, promote immune tolerance, increase pancreatic β-cell proliferation and regeneration, increase insulin secretion, improve insulin sensitivity, increase energy utilization, and reverse TIDM, via up regulation of its target gene, 18/April/2018, 10.40 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]

April 18, 2018

Published by admin_auro at April 18, 2018

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Bonding your way to keep cardiac diseases at bay: Oxytocin-based intranasal inhalation therapy for cardiac rejuvenation: Oxytocin, a peptide hormone and neuropeptide known to play a role in empathy, generosity, child birth and so on, suppresses tumor suppressor INK4a/p16 expression, and inhibits dilated cardiomyopathy via up regulation of its target gene, 18/April/2018, 10.17 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: A noble way to keep cardiac diseases at bay: Noble gas xenon-based cardiac […]

April 18, 2018

Published by admin_auro at April 18, 2018

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Cancer
Ideas

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, increases the expression of tumor suppressors genes, such as PTEN, PDCD4, INK4a, BTG2, TA-p73/p63, TPM1, TIMP3, CCM1/KRIT1 and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 18/April/2017, 9.55 pm

From Significance of the study to Public health relevance: Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]

April 18, 2018

Published by admin_auro at April 18, 2018

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Treating blood sugar disease with antidepressants: Duloxetine-based therapy for diabetes (TIIDM): Duloxetine (Brand name: Cymbalta), used in the treatment of major depressive disorder, generalized anxiety disorder, fibromyalgia, neuropathic pain and others, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/April/2018, 9.49 pm

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, […]