Ideas

Hydrogen gas inhalation therapy for Cardiomyopathy: Inhalation of Hydrogen gas decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins, and alleviates Cardiomyopathy, via up regulation of its target gene, 19/March/2019, 6.23 am
Hydrogen gas inhalation therapy for Cardiomyopathy: Inhalation of Hydrogen gas decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins, and alleviates Cardiomyopathy, via up regulation of its target gene, 19/March/2019, 6.23 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Hinokitiol as a broad-spectrum anti-infective agent: Hinokitiol, one of the main components of Cypress leaves,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 14/March/2019,  6.07 am
Hinokitiol as a broad-spectrum anti-infective agent: Hinokitiol, one of the main components of Cypress leaves,  inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 14/March/2019,  6.07 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Combinatorial therapy for Deafness: A therapeutic mix encompassing LncRNA HOTAIR, Cholecalciferol, Ajoene and DIM (HCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via upregulation of its target genes, 16/March/2019, 5.58 am
Combinatorial therapy for Deafness: A therapeutic mix encompassing LncRNA HOTAIR, Cholecalciferol, Ajoene and DIM (HCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via upregulation of its target genes, 16/March/2019, 5.58 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Combinatorial therapy for Deafness: A therapeutic mix encompassing LncRNA HOTAIR, Cholecalciferol, Ajoene and DIM (HCAD)  increases the expression of ATG5 (Autophagy-related…

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Repurposing the known anti-hyperglycemic drug Sitagliptin into a stroke medicine: Sitagliptin (brand name: Januvia, Tesavel, Xelevia, and others ), used to bring down high blood glucose levels in Type II diabetes patients, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 16/March/2019, 5.46 am
Repurposing the known anti-hyperglycemic drug Sitagliptin into a stroke medicine: Sitagliptin (brand name: Januvia, Tesavel, Xelevia, and others ), used to bring down high blood glucose levels in Type II diabetes patients, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 16/March/2019, 5.46 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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Ribonucleic acid-based therapy for glaucoma:  LncRNA DGCR5 increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 16/March/2019, 5.30 am
Ribonucleic acid-based therapy for glaucoma:  LncRNA DGCR5 increases Nmnat1 expression, increases NAD+ levels, improves neuronal dysfunction, and protects against glaucoma,  via down regulation of its target gene, 16/March/2019, 5.30 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the The Jackson Laboratory, Bar Harbor, ME 04609, USA; Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, USA; The Howard Hughes…

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Epicatechin-3-gallate(ECG)-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epicatechin-3-gallate(ECG), one of the main components of green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 16/March/2019, 5.23 am
Epicatechin-3-gallate(ECG)-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epicatechin-3-gallate(ECG), one of the main components of green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 16/March/2019, 5.23 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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