Ideas

April 24, 2019

Published by admin_auro at April 24, 2019

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Canagliflozin-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Canagliflozin (Brand name: Invokana, Sulisent, Prominad), a Sodium-glucose co-transporter 2 inhibitor used to treat TIIDM, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes, via up-regulation of its target gene, 24/April/2019, 7.37 am

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]

April 24, 2019

Published by admin_auro at April 24, 2019

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Ideas
Stroke

Erythropoietin/Haematopoietin-derived peptide functions as a stroke medicine: Cyclic helix B peptide (CHBP), derived from Erythropoietin/Haematopoietin, attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits, via up-regulation of its target genes BDNF and NAMPT, 24/April/2019, 5.56 am

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; […]

April 22, 2019

Published by admin_auro at April 22, 2019

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Mechanistic insights into how Edaravone aids in recovery from stroke: Edaravone (brand name: Radicut, Radicava, Xavron, Edavit, others), used in the treatment of stroke and amyotrophic lateral sclerosis, increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 23/April/2019, 12.14 am

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

April 22, 2019

Published by admin_auro at April 22, 2019

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Mechanistic insights into how bariatric surgery aids in control of body weight, energy homeostasis, and TIIDM: Bariatric surgery increases REV-ERB and its downstream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 22/April/2018, 11.35 pm

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]