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Ideas

August 22, 2018
Published by admin_auro at August 22, 2018
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Combinatorial  therapy for human cancers: A pharmaceutical mixture encompassing Metformin, Berberine, Despiramine, 17-AAG, Curcumin, Calcitriol, Capsaicin, Camptothecin, Simvastatin, Salinomycin, (MBDAAGCCCSS) inhibits the expression of KAT6A and KAT6B, increases the expression of INK4a/ARF and other genes, promotes senescence, prevents cancer recurrence, and prolongs survival, via up-regulation of its target gene, 22/August/2018, 7.35  am

Introduction: What they say: A study from the Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; The Walter and Eliza Hall […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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Combinatorial therapy for Metastatic ovarian cancers: A therapeutic mix encompassing  Metformin, 17-AAG, Carboplatin, Despiramine, Simvastatin, and Salinomycin (MAAGCDSS) inhibits the expression of FABP4, increases the expression of a number of tumor suppressor genes, and stifles the metastatic potential and the progression of ovarian cancers, via up-regulation of its target gene, 22/August/2017, 7.21 am

Introduction: What they say: A study from the Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, 77030, […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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Molecular therapy for cardiomyocyte proliferation and heart regeneration: Nucleolin, a nucleolar protein, decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 22/August/2018, 7.07 am

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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The female steroid hormone functions as a longevity promoter: 17α-Estradiol (trade name: Avicis, Avixis, Ell-Cranell Alpha, and Pantostin), the c-17 epimer of Estradiol,  may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 22/August/2018, 6.31 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
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