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Ideas

August 6, 2018

TB vaccine for learning/memory/cognitive-enhancement (neither mocking nor joking, but presenting with mindful mechanistic insights, supported by scientific evidences) therapy: TB/BCG vaccine, a tuberculosis vaccine,  increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target gene, 6/August/2018, 2.08 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA;  Paul F. Glenn Center […]
August 6, 2018

A sweet way to treat anxiety and depression:  D-Allose,  an aldohexose sugar and C-3 epimer of glucose, decreases PHF8 levels, increases the expression of serotonin receptors Htr1a and Htr2a, and promotes resistance to stress-induced -anxiety and -depression, via down-regulation of its target gene, 6/August/2018, 1.43 pm

Introduction: What they say:  A study from Department of Molecular Biology, Cancer Center and Center for Regenerative Medicine, Massachusetts General Hospital, Boston, Massachusetts 02114, USA; Department […]
August 6, 2018

Flu vaccine for pain therapy: Influenza A (H1N1)/Flu vaccine-based activation of the PD-1 pathway for Pain therapy:  Influenza A (H1N1)/Flu vaccine increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 6/August/2018, 7.40 am

 Introduction: What they say: A recent study, from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]
August 4, 2018

Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as LATS1, SMARCA4, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 8/August/2018, 11.51 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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