Ideas

April 6, 2019

Published by admin_auro at April 6, 2019

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Eat oats to stay free of infections caused by chikungunya (CHIKV) and Zika (ZIKV) viruses: Oats-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Avenanthramide-A, derived from Oats, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 6/April/2019, 12.43 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]

April 5, 2019

Published by admin_auro at April 5, 2019

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Cancer
Ideas

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as BIRC5, PIAS3, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 5/April/2019, 11.14 pm

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that: Probiotic-based chemotherapy targeting cancer stem cells […]

April 5, 2019

Published by admin_auro at April 5, 2019

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Ribonucleic acid-based therapy for enhancing memory and cognition: LncRNA BANCR increases Tissue inhibitor of metalloproteinases 2 (TIMP2) levels, improves cognition, and decreases age-associated decline in memory and learning, via down-regulation of its target genes, 5/April/2019, 11.07 pm

Introduction: What they say: A study from Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, California 94305, USA; Paul F. Glenn Center […]

April 5, 2019

Published by admin_auro at April 5, 2019

Categories

Ideas
Pain

Mechanistic insights into how Opioids function as pain medication: Endorphin-2, an endogenous opioid, increases the expression of PD-L1, attenuates acute and chronic pain, and suppresses mechanical and thermal hypersensitivity and inhibits nociceptive neuron excitability, via up-regulation of its target gene, 5/April/2019, 10.58 pm

Introduction: What they say: A recent study from Institute of Neurobiology, Institutes of Brain Science and State Key Laboratory of Medical Neurobiology, Collaborative Innovation Center for […]