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Longevity

July 18, 2018

Flavonoid your way to decrease blood pressure/sugar and extend lifespan: Quercetin-based Lifespan and healthspan extension therapy: Quercetin,  a flavonoid isolated from elder berries and onions, decreases blood sugar and blood pressure levels and prolongs mammalian life span, via down regulation of angiotensin II type I receptor (AT1R), 18/July/2018, 7.47 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]
July 18, 2018

Heat-shock inhibitors (HSPs) as longevity-promoters: HSP-90 inhibitor-based combinatorial therapy for Lifespan extension: A therapeutic mix encompassing 17-DMAG(HSP-90 inhibitor), Ursolic acid, Catalpol, Isoliquiritigenin, Maresin, DIM, Lutein, Maresin, Cholecalciferol (17-DMAGUCIMDLMC) activates autophagy, promotes leanness, increases insulin sensitivity, improves motor function, alleviates ageing feature and extends lifespan, via up regulation of its target gene ATG5 (Autophagy related 5), 18/July/2018, 7.34 am

Introduction: What they say A study from the Global Research Laboratory, Seoul National University, Korea shows that “Overexpression of Atg5 in mice activates autophagy and extends lifespan.” This study was […]
July 12, 2018

Inhibitors of heat shock response as longevity-promoters: 17-DMAG, a heat shock protein-90 (HSP-90) inhibitor, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 12/July/2017, 1.20 pm

What they say?  A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]
July 12, 2018

A flavonoid way to lengthen lifespan: Quercetin, a flavonoid isolated from elder berries, onions and others,  may  increase insulin sensitivity, slow down cardiac aging, and increase life span, via up-regulation of BubR1 and others genes, 12/July/2018, 12.53 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]