December 29, 2017

Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Nateglinide, an anti-hyperglycemic drug,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 29/December/2017, 11.12 pm

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
December 27, 2017

Lifespan extension therapy: Hydralazine[Trade name: Apresoline], used in the treatment of high blood pressure and heart attacks,  increases life span via up-regulation of its target gene BubR1, 28/December/2017, 1.03 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
December 27, 2017

Natural product-based Anti-ageing and Life extension therapy:  A pharmaceutical mixture encompassing Apigenin and Chrysin increases CHIP levels, increases monoubiquitylation of insulin receptor (INSR), decreases INSR protein levels and enhances lifespan via down regulation of its target gene, 28/December/2017, 12.54 am

Introduction: What they say A study from Institute for Cell Biology, University of Bonn, Ulrich-Haberland Str.  Bonn, Germany; and Institute for Genetics and CECAD Research Center, […]
December 26, 2017

Lifespan extension therapy: Lycopene, the commonly found Carotene in Gac, Guava, and Tomatoes, among others, prolongs mammalian life span via down regulation of angiotensin II type I receptor (AT1R), 26/December/2017, 7.44 am

Significance of the study: It has been shown earlier that antagonizing angiotensin II type I receptor (AT1R) expression may prolong mammalian life span. Further, it has been shown […]