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Malaria

September 18, 2018

Anesthetic drug comes to the rescue of blood-stage Plasmodium infection: Procaine (PCA) (trade name: Novocain), a local anesthetic drug,  decreases the expression of CTLA-4, PD-L1, and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up-regulation of its target gene, 18/September/2018, 7.35 am

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
August 13, 2018

Contraceptive pills may aid in the treatment of blood-stage Plasmodium infection: Progestin, one of the components of birth control/contraceptive pills, decreases the expression of CTLA-4, PD-L1, and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via upregulation of its target gene, 13/August/2018, 6.52 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
July 27, 2018

β-glucan comes to the rescue of blood-stage Plasmodium infection:  β-(1,3)-glucan (LNT), isolated from mushroom Lentinus edodes,  decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up-regulation of its target gene, 27/July/2018, 11.08 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]
July 17, 2018

Anti-hyperglycemic drug comes to the rescue of blood-stage Plasmodium infection: Ciglitazone, an anti-hyperglycemic drug,  decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 17/July/2018, 5,50 pm

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]