Metabolic disease

Amino acid-based therapy for body weight control, energy homeostasis and TIIDM: L-Arginine, a non-essential amino acid that aids in blood flow and in maintaining optimal nitric oxide levels, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 8/March/2018, 6.36 am
Amino acid-based therapy for body weight control, energy homeostasis and TIIDM: L-Arginine, a non-essential amino acid that aids in blood flow and in maintaining optimal nitric oxide levels, increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 8/March/2018, 6.36 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour and metabolism by synthetic…

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Natural product-based exercise mementics therapy for Metabolic disease: 18β-Glycyrrhetinic acid [(18β-GA) Enoxolone], isolated from glycyrrhiza glabra/Licorice, increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 27/January/2018, 11.41 pm
Natural product-based exercise mementics therapy for Metabolic disease: 18β-Glycyrrhetinic acid [(18β-GA) Enoxolone], isolated from glycyrrhiza glabra/Licorice, increases PPARδ  and Foxo1 levels, inhibits glucose catabolism, preserves glucose levels, stimulates FA catabolism, delays the onset of hypoglycemia and boosts endurance exercise via down regulation of its target gene, 27/January/2018, 11.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Department of Molecular Medicine, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA shows that “CRY1/2 Selectively Repress…

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Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor suppressors PDCD4 and PTEN, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 10/January/2017, 6.52 pm
Molecular therapy for Metastatic cancers: Torasemide, an anti-hypertensive drug, increases the expression of tumor suppressors PDCD4 and PTEN, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 10/January/2017, 6.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more than half of them…

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Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am
Molecular therapy for TIIDM and Metabolic defects: Ezetimibe (Trade name: Zetia or Ezetrol), a cholesterol lowering medication, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 31/October/2017, 11.11 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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Natural product therapy for body weight control, energy homeostasis and TIIDM: A therapeutic mix encompassing Berberine, Leucine and Genistein (BLG) increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 10/October/2017,11.35 pm
Natural product therapy for body weight control, energy homeostasis and TIIDM: A therapeutic mix encompassing Berberine, Leucine and Genistein (BLG) increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 10/October/2017,11.35 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour and metabolism by synthetic…

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Natural product-based combinatorial therapy for TIIDM, Metabolic defects and Longevity: A therapeutic mix encompassing Nordihydroguaiaretic acid (NDGA) & Mangosteen  (NDGAM) increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 04/October/2017, 1.53 am
Natural product-based combinatorial therapy for TIIDM, Metabolic defects and Longevity: A therapeutic mix encompassing Nordihydroguaiaretic acid (NDGA) & Mangosteen  (NDGAM) increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 04/October/2017, 1.53 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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