Obesity and body weight control

April 29, 2019

Oxyntomodulin-based therapy for lowering cholesterol, and triglycerides levels: Oxyntomodulin (OXM), a 37 amino acid intestinal peptide that  inhibits food intake and body weight, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 29/April/2019, 2.58 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
April 27, 2019

Hunger hormone-based therapy for lowering cholesterol, and triglycerides levels: Ghrelin, a digestive hormone that controls appetite, decreases the levels of HMGCR,  triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via up-regulation of its target gene, 27/April/2019, 11.57 pm

The significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 […]
February 6, 2019

Amino acid-based therapy for body weight control, energy homeostasis, and TIIDM: Amino acid L-Alanine  increases REV-ERB and its downstream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 6/February/2019, 11.42 pm

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behavior […]
February 5, 2019

Probiotic-based therapy for body weight control, energy homeostasis, and TIIDM: Probiotic Clostridium butyricum MIYAIRI 588 (CBM588)  increases REV-ERB and its downstream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 5/February/2019, 10.17 pm

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour […]