Check our Recent Posts
Total no of Ideas: 11176
Empagliflozin-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Empagliflozin(EMBA) (Brand name: Jardiance), a drug used in the treatment of TIIDM, increases the expression of ERBB2/Her2 and promotes dedifferentiation of cardiomyocytes, via up-regulation of its target gene, 14/February/2018, 10.54 pm
Ribonucleic acid-based therapy for aging-associated diseases and Lifespan extension: LncRNA DANCR inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and aging, via down-regulation of its target gene, 14/February/2019, 6.48 am
Combinatorial therapy for gynecologic cancers: A therapeutic mix encompassing Simvastatin and Navitoclax (ABT-263) (SAN) inhibits the expression of HDAC6, acetylates tumor suppressor proteins, activates tumor suppressor function, and stifles the progression of ARID1A-mutated ovarian cancers, via up-regulation of its target gene, 14/February/2019, 6.29 am
Molecular therapy for Malaria: Probucol, a drug used in the treatment of dyslipidemia, increases Ferroportin expression, decreases intracellular iron accumulation, inhibits cellular damage, prevents hemolysis, and inhibits malaria infection, via upregulation of its target gene, 14/February/2019, 6.21 am
Ribonucleic acid-based therapy for aging-associated diseases and Lifespan extension: LncRNA PCGEM1 (Prostate-specific transcript 1) inhibits the interaction of DBC1 with PARP1, increases the PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer, and ageing, via down-regulation of its target gene, 12/February/2019, 11.14 pm
Combinatorial therapy for cancer: A therapeutic mix encompassing Metformin and Navitoclax/ABT-263 (MAN) increases the expression of mitochondrial protein LACTB, decreases levels of mitochondrial phosphatidylserine decarboxylase, alters mitochondrial lipid metabolism, and promotes differentiation of breast cancer cells via up-regulation of its target gene, 12/February/2018, 10.31 pm
Natural product-derived Combination therapy for Squamous cell carcinoma of head and neck (HNSCC): A therapeutic mix encompassing a therapeutic mix encompassing Metformin and Navitoclax/ABT-263 inhibits BMI1 and AP-1 expression, overcomes chemotherapeutic resistance, promotes chemosensitivity, suppresses cancer stem cells in HNSCC, and inhibits lymph node metastasis, via down-regulation of its target genes, 12/February/2017, 10.13 pm
Combinatorial therapy for Metastatic human tumors: A pharmaceutical mixture encompassing metformin and Navitoclax/ABT-263 (MAN) decreases the expression of c-Src protein, inhibits the expression of a number of enzymes in glycolytic cycle, and suppresses proliferation, migration, invasion, tumorigenesis and metastasis via upregulation of its target gene, 11/February/2017, 12.34 am
Who we are and what we do
Ideas can even be life changing.
We generate bio-medical/pharma/therapeutic/clinical ideas for the scientific community. Good Ideas are uncommon and unique. This is because everyone’s educational background is different. As a result, every one’s thinking process is different. Consequently, his/her ability to connect/understand complex biological/pathological mechanism differs.