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Total no of Ideas: 11682

May 9, 2020

Published by admin_auro at May 9, 2020

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Hypertonic saline-based Prophylatic therapy for SARS-COV-2/COVID-19: Hypertonic saline (Nacl) inhibits SARS-COV-2/1, Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, Foot and Mouth disease, ADV, Respiratory Syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, Interferon-stimulated gene 15, and others 10/May/2020, 12.50am

April 14, 2020

Published by admin_auro at April 14, 2020

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Hyperthermia-based Prophylatic therapy against SARS-COV-2/COVID-19: Hyperthermia (40C to 43C) inhibits SARS-COV-2/1, Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, Foot and Mouth disease, ADV, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, Interferon-stimulated gene 15, and others 15/April/2020, 12.27 am

April 12, 2020

Published by admin_auro at April 12, 2020

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A potential vaccine against SARS-COV-2: Repurposing the IB-ND Virus-like particles (VLPs) vaccine into a Prophylactic IB-ND VLPs-COVID-19 vaccine: A novel chimeric infectious bronchitis-Newcastle disease (IB-ND) virus-like particles (VLPs) inhibit SARS-COV-2/1, Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, Foot and Mouth disease, ADV, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, Interferon-stimulated gene 15, and others 12/April/2020, 11.01 pm

April 5, 2020

Published by admin_auro at April 5, 2020

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A vaccine against SARS-COV-2: Repurposing the Influenza A (H1N1)/Flu vaccine into a Prophylactic Flu-COVID-19 vaccine: Influenza A (H1N1)/Flu vaccine inhibits SARS-COV-2, Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, Foot and Mouth disease, ADV, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, Interferon-stimulated gene 15, and others 5/April/2020, 3.14 pm

March 31, 2020

Published by admin_auro at March 31, 2020

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A vaccine against SARS-COV-2: Repurposing the tuberculosis BCG vaccine into a Prophylactic COVID-19 vaccine: BCG vaccine inhibits SARS-COV-2, Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1, respiratory syncytial, Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, Interferon-stimulated gene 15, and others 1/April/2020, 1.29 am

March 10, 2020

Published by admin_auro at March 10, 2020

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Repurposing the anti-asthmatic drug Montelukast into an anti-tuberculosis drug: Montelukast (trade name: Singulair) deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via upregulation of its target gene, 10/March/2020, 8.01 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]

March 10, 2020

Published by admin_auro at March 10, 2020

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Anti-asthmatic drug comes to the rescue of blood-stage Plasmodium infection: Pranlukast, an anti-asthmatic drug, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clears blood-stage malaria, via up regulation of its target gene, 10/March/2020, 7.38 am

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that […]

March 10, 2020

Published by admin_auro at March 10, 2020

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Mechanistic insights into how Vitamin D3/Cholecalciferol enhances immunity against bacterial infections: Cholecalciferol-based immune enhancement therapy: Low dose Cholecalciferol/Vitamin-D3 increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 10/March/2020, 6.18 am

Introduction: What they say: A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in […]

March 9, 2020

Published by admin_auro at March 9, 2020

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Repurposing the anti-hypertensive drug Carvedilol into an antiviral agent: Carvedilol (trade name: Coreg), increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 10/March/2019, 12.02 am

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]

March 9, 2020

Published by admin_auro at March 9, 2020

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Antiviral therapy against Neuroinvasive West Nile virus: Zafirlukast, an anti-asthmatic drug, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 9/March/2020, 11.42 pm

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of […]

March 9, 2020

Published by admin_auro at March 9, 2020

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Repurposing the anti-cancer agent Imatinib into an anti-HIV agent: Imatinib (trade name: Gleevec, Glivec and others) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 9/March/2020, 11.23 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-cancer agent Imatinib into an anti-HIV agent: Imatinib (trade name: Gleevec, […]

March 9, 2020

Published by admin_auro at March 9, 2020

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Curing, preventing and reversing diabetes with a commonly available antiasthmatic drug Montelukast: Montelukast-based therapy for TIIDM and obesity-associated metabolic deficits: Montelukast (trade name: Singulair and others), a vasodilator used in the treatment of asthma, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, decreases TXNIP expression, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 9/March/2020, 11.08 pm

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]

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Who we are and what we do

About us

Ideas can even be life changing.

We generate bio-medical/pharma/therapeutic/clinical ideas for the scientific community. Good Ideas are uncommon and unique. This is because everyone’s educational background is different. As a result, every one’s thinking process is different. Consequently, his/her ability to connect/understand complex biological/pathological mechanism differs.

Dr L. Boominathan Ph.D.

President & Director-cum-Chief scientist

Dr Boominathan was the first one in the world to propose a p73/p63-dependent cancer suppressor pathway (Supported by a legally valid Invention disclosure document certified by an advocate-2002/3)

Check our Recent Posts

Total no of Ideas: 11682

Who we are and what we do

About us

Dr L. Boominathan Ph.D.

Dr Boominathan’s quote on Science

Science is not about how to follow the conventions, but about how not to follow the conventions