Antiviral diseases

Repurposing the analgesic agent Parecoxib into an anti-HIV agent: Parecoxib (trade name: Dynastat), a selective cox-2 (Cyclooxygease-2) inhibitor, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 11/october/2018, 12.14 am
Repurposing the analgesic agent Parecoxib into an anti-HIV agent: Parecoxib (trade name: Dynastat), a selective cox-2 (Cyclooxygease-2) inhibitor, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 11/october/2018, 12.14 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the analgesic agent Parecoxib into an anti-HIV agent: Parecoxib (trade name: Dynastat), a selective cox-2 (Cyclooxygenase-2) inhibitor,…

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Consuming good bacteria (Probiotic) may eliminate bad microbes: Probiotic Lactobacillus Rhamnosus-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Probiotic Lactobacillus Rhamnosus increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 23/September/2018, 1.46 pm
Consuming good bacteria (Probiotic) may eliminate bad microbes: Probiotic Lactobacillus Rhamnosus-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Probiotic Lactobacillus Rhamnosus increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 23/September/2018, 1.46 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Probiotics as anti-infective agents:  Probiotics-based adjunct therapy for viral and bacterial infections: Probiotic Lactobacillus Rhamnosus inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 21/September/2018, 10.29 pm
Probiotics as anti-infective agents:  Probiotics-based adjunct therapy for viral and bacterial infections: Probiotic Lactobacillus Rhamnosus inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene, 21/September/2018, 10.29 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via upregulation of its target gene, 13/August/2018, 6.28 pm
An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via upregulation of its target gene, 13/August/2018, 6.28 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: An aspirin a day keeps HIV1-infections at bay: Aspirin, an analgesic/antipyretic drug, increases Heme oxygenase 2 (HO-2) expression,…

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Birth control/contraceptive pills as anti-infective agents:  17-α-Ethynylestradiol, one of the main components of contraceptive/birth control pills, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 131/August/2018, 6.11 pm
Birth control/contraceptive pills as anti-infective agents:  17-α-Ethynylestradiol, one of the main components of contraceptive/birth control pills, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 131/August/2018, 6.11 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Deoxy sugar-based anti-infective Therapy: D Rhamnose β-hederin (DRβ-H), isolated from Clematis ganpiniana, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 1/August/2018,  9.54 pm
Deoxy sugar-based anti-infective Therapy: D Rhamnose β-hederin (DRβ-H), isolated from Clematis ganpiniana, inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 1/August/2018,  9.54 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

read more
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