Repurposing the analgesic agent Parecoxib into an anti-HIV agent: Parecoxib (trade name: Dynastat), a selective cox-2 (Cyclooxygease-2) inhibitor, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 11/october/2018, 12.14 am