Antiviral diseases

Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am
Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore shows…

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Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am
Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 24/September/2017, 11.59 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Antiviral therapy for HIV virus: Combvir [Zidovudine (ZDV)/Azidothymidine (AZT) and Lamivudine], an anti-HIV drug, increases Heme oxygenase 2 (HO-2) expression, blocks…

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Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Solosodine, isolated from Solanum melongena L, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 24/September/2017, 11.53pm
Natural product-derived antiviral therapy against Neuroinvasive West Nile virus: Solosodine, isolated from Solanum melongena L, increases the expression of RIPK3, promotes chemokines production, inhibits neuroinflammation, and restricts neuroinvasive West Nile virus production and pathogenesis in neurons via up regulation of its target gene, 24/September/2017, 11.53pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Immunology, University of Washington, Seattle, WA 98109, USA; Center for Innate Immunity and Immune Disease, University of Washington, Seattle, WA 98109,…

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Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm
Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Epigallocatechin gallate (EGCG), isolated from Green tea, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 24/September/2017, 11.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Antiviral therapy for Hepatitis-B virus: Suramin increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 23/September/2017,  1.56 pm
Antiviral therapy for Hepatitis-B virus: Suramin increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 23/September/2017,  1.56 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058,…

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Antiviral therapy for Hepatitis-B virus: Sodium Selenite increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 21/September/2017,  10.41 pm
Antiviral therapy for Hepatitis-B virus: Sodium Selenite increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 21/September/2017,  10.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China; and Institute of Immunology, Zhejiang University School of Medicine, Hangzhou 310058,…

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