Antiviral diseases

October 9, 2017

Antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: A pharmaceutical mixture encompassing Artesunate and 15-Deoxy-Delta-12,14-prostaglandin J2 (15d-PGJ2) [APGJ2] increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via up regulation of its target gene, 09/October/2017, 11.29 pm

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex […]
October 2, 2017

Natural product-derived antiviral therapy against Hepatitis-B virus: Protocatechuic acid (PCA) , found abundantly in Allium cepa (Onion), and roselle, among others, increases the expression of Setd2, methylates STAT1, activates STAT1, promotes trimethylation of IFN-stimulated gene-15, and restricts Hepatitis-B virus (HBV) production and pathogenesis via up regulation of its target gene, 02/October/2017,  11.59 pm

On the eve of Mahatma Gandhi Birth Anniversary ********* We wish everyone a happy Mahatma Gandhi Jayanti 2017. On this special occasion, we are happy to announce that Ideas posted today (02/October/2017) will […]
September 28, 2017

Natural product-derived antiviral therapy for HIV virus: Nordihydroguaiaretic acid (NDGA), isolated from creosote, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production via up regulation of its target gene, 29/September/2017, 12.40 am

Introduction: What they say A study from the Department of Biochemistry and Molecular Biophysics and Department of Microbiology and Immunology, Howard Hughes Medical Institute, Columbia University, […]
September 24, 2017

Natural product-derived therapy for tuberculosis: Withaferin A (WA), isolated form Ashwagantha/Withania sominifera, deacetylates RelA/p65, inhibits inflammatory gene expression downstream of RelA/p65, inhibits TB pathogenesis, increases the efficacy of anti-TB drug, and promotes M. tuberculosis clearance via up regulation of its target gene, 25/September/2017, 12.05 am

Introduction: What they say: A study from the Singapore Immunology Network, Agency for Science, Technology and Research, Singapore; and Lee Kong Chian School of Medicine, Nanyang […]