Antiviral diseases

Repurposing the anti-asthmatic agent Tranilast into an anti-HIV agent: Tranilast (trade name: Rizaben and others) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 26/February/2020, 11.07 pm
Repurposing the anti-asthmatic agent Tranilast into an anti-HIV agent: Tranilast (trade name: Rizaben and others) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 26/February/2020, 11.07 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-asthmatic agent Tranilast into an anti-HIV agent: Tranilast (trade name: Rizaben and others) increases Heme…

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Repurposing the anti-hypertensive agent Carvedilol into an anti-HIV agent: Carvedilol (trade name: Coreg and others)) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 22/February/2020, 11.19 pm
Repurposing the anti-hypertensive agent Carvedilol into an anti-HIV agent: Carvedilol (trade name: Coreg and others)) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 22/February/2020, 11.19 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-hypertensive agent Carvedilol into an anti-HIV agent: Carvedilol (trade name: Coreg and others)) increases Heme…

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Repurposing the anti-lipidemic agent Fenofibrate into an anti-HIV agent: Fenofibrate  (trade name: Fenoglide, Lipofen, Tricor and others)), an antilipidemic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 20/February/2020, 9.39 am
Repurposing the anti-lipidemic agent Fenofibrate into an anti-HIV agent: Fenofibrate  (trade name: Fenoglide, Lipofen, Tricor and others)), an antilipidemic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 20/February/2020, 9.39 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-lipidemic agent Fenofibrate into an anti-HIV agent: Fenofibrate  (trade name: Fenoglide, Lipofen, Tricor and others)), an…

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Sunshine vitamin functions as a broad-spectrum anti-infective agent: Calcitriol/Cholecalciferol (1,25-dihydroxyvitamin D3)/Tacalcitol inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 4/September/2019,  10.19 pm
Sunshine vitamin functions as a broad-spectrum anti-infective agent: Calcitriol/Cholecalciferol (1,25-dihydroxyvitamin D3)/Tacalcitol inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 4/September/2019,  10.19 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA shows that “The IFITM proteins…

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Where eating the peel will protect you against viral diseases than the pulp (fruit): Citrus peel-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Hesperidin, Tangeretin & Nobiletin (HTN), isolated from citrus flavonoid purity mixture or citrus peels, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 17/July/2019, 10.40 pm
Where eating the peel will protect you against viral diseases than the pulp (fruit): Citrus peel-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Hesperidin, Tangeretin & Nobiletin (HTN), isolated from citrus flavonoid purity mixture or citrus peels, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication via upregulation of its target gene, 17/July/2019, 10.40 pm 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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Mechanistic insights into how Ginger-derived compounds function as antiviral agents: Ginger-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Zingerone, isolated from Ginger, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 4/June/2019, 11.01 am
Mechanistic insights into how Ginger-derived compounds function as antiviral agents: Ginger-based antiviral therapy for chikungunya (CHIKV) and Zika (ZIKV) viruses: Zingerone, isolated from Ginger, increases spermidine/spermine N1-acetyltransferase (SAT) expression, depletes spermidine and Spermine levels, and restricts Chikungunya and Zika viruses replication, via upregulation of its target gene, 4/June/2019, 11.01 am 1280 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Viral Populations and Pathogenesis Unit, Institut Pasteur, CNRS UMR 3569, 25–28 rue du Dr. Roux, 75724 Paris Cedex 15, France shows that…

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