Antiviral diseases

February 26, 2020

Repurposing the anti-asthmatic agent Tranilast into an anti-HIV agent: Tranilast (trade name: Rizaben and others) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 26/February/2020, 11.07 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-asthmatic agent Tranilast into an anti-HIV agent: Tranilast (trade name: Rizaben […]
February 22, 2020

Repurposing the anti-hypertensive agent Carvedilol into an anti-HIV agent: Carvedilol (trade name: Coreg and others)) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 22/February/2020, 11.19 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-hypertensive agent Carvedilol into an anti-HIV agent: Carvedilol (trade name: Coreg […]
February 20, 2020

Repurposing the anti-lipidemic agent Fenofibrate into an anti-HIV agent: Fenofibrate  (trade name: Fenoglide, Lipofen, Tricor and others)), an antilipidemic drug, increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 20/February/2020, 9.39 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Repurposing the anti-lipidemic agent Fenofibrate into an anti-HIV agent: Fenofibrate  (trade name: Fenoglide, Lipofen, […]
September 4, 2019

Sunshine vitamin functions as a broad-spectrum anti-infective agent: Calcitriol/Cholecalciferol (1,25-dihydroxyvitamin D3)/Tacalcitol inhibits Hepatitis-B/C, Dengue, Zika, Ebola, HIV-1, Mtb, Malaria, CMV, Influenza H1NI1,  respiratory syncytial,  Sindbis, and SFV viruses by increasing the Levels of the Antiviral Proteins IFITM3, & Interferon-stimulated gene 15, 4/September/2019,  10.19 pm

Introduction: What they say: A study from the Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard Medical School, Charlestown, MA 02129, USA […]