Autoimmune diabetes

August 20, 2019

Natural product-based curative therapy for autoimmune diabetes  (TIDM):  Repurposing the anti-malarial drug Artesunate into an anti-diabetic drug:  Artesunate, a derivative of Artimesinin, which aids in the treatment of malaria, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 20/August/2019, 10.09 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
July 5, 2019

Curing autoimmune diabetes  (TIDM) with HDAC (Histone deacetylase) inhibitors: Givinostat/Gavinostat-based therapy for autoimmune diabetes:Givinostat/Gavinostat, a histone deacetylase inhibitor used to treat systemic juvenile idiopathic arthritis,polycythaemia vera., Duchenne muscular dystrophy and others, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 5/July/2019, 11.19 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
July 4, 2019

Curing autoimmune diabetes  (TIDM) with interleukin 1 receptor antagonists:Anakinra-based therapy for autoimmune diabetes: Anakinra (brand name: Kineret and others),  an interleukin 1 receptor antagonist used in the treatment of rheumatoid arthritis, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up-regulation of its target gene, 4/July/2019, 11.03 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
July 4, 2019

Rotavirus Vaccine-based curative therapy for autoimmune (Type I) diabetes (TIDM):  Rotavirus vaccine promotes the expression of PD-L1, attenuates the expression of tumor suppressor TXNIP, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 4/July/2019, 8.17 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]