Cancer metastasis

April 22, 2018

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Dexoycholic acid increases the expression of tumor suppressors genes, such as TA-p73/p63, TPM1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 22/April/2017, 11.29 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
April 22, 2018

Therapeutic insights into “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: Amitriptyline (trade name: Elavil), a medication used to treat major depressive disorder, anxiety disorder, and bipolar disorder, increases the expression of tumor suppressors genes, such as TIMP3, CCM3/KRIT1, TA-p73/p63, TPM1, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 22/April/2017, 11.24 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
April 21, 2018

Turning on the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, increases the expression of tumor suppressors genes, such as GRHL3, long ncRNA Gas5, BigH3, TIPE2, PTEN, PDCD4, INK4a, BTG2, TA-p73/p63, TPM1, TIMP3, CCM1/KRIT1 and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 21/April/2017, 8.00 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
April 20, 2018

Turning on the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, increases the expression of tumor suppressors genes, such as BigH3, TIPE2, PTEN, PDCD4, INK4a, BTG2, TA-p73/p63, TPM1, TIMP3, CCM1/KRIT1 and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 20/April/2017, 2.42 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]