Cancer metastasis

June 17, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as SMARCA4, KIBRA, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 17/June/2019, 5.48 am

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in chronic lymphocytic leukemia (CLL) and advanced metastatic cancers: A pharmaceutical mixture encompassing Venetoclax and Ibrutinib (VAI) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as SMARCA4, KIBRA, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, and stalls CLL progression, via up-regulation of its target gene, 17/June/2019, 5.48 am https://genomediscovery.org/wp-content/uploads/2019/06/VAI-and-or-the-probiotic-Lactobacillus-increases-the-expression-of-SMARCA4-KIBRA-and-other-genes-and-attenuates-tumor-progression.jpg4_.jpg 1280 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/06/VAI-and-or-the-probiotic-Lactobacillus-increases-the-expression-of-SMARCA4-KIBRA-and-other-genes-and-attenuates-tumor-progression.jpg4_.jpg June 17, 2019 June 17, 2019

Introduction: What they say A study from the University of Texas M.D. Anderson Cancer Center, Houston, USA shows that “Ibrutinib and Venetoclax for First-Line Treatment of CLL.” This research paper was published, in…

April 18, 2019

An aspirin a day keeps metastatic cancer away, if so, what is the mechanism?: Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing Aspirin, a nonsteroidal anti-inflammatory drug, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as E-cadherin, PDCD4, BIRC5, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 18/April/2019, 10.41 pm

An aspirin a day keeps metastatic cancer away, if so, what is the mechanism?: Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing Aspirin, a nonsteroidal anti-inflammatory drug, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as E-cadherin, PDCD4, BIRC5, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 18/April/2019, 10.41 pm https://genomediscovery.org/wp-content/uploads/2019/04/A-pharmaceutical-mixture-encompassing-Aspirin-and-probiotic-Lactobacillus-fns-as-antimetastasis-agent-by-increasing-BIRC5-PDCD4-p53-TAp73-TAp63-and-others.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/04/A-pharmaceutical-mixture-encompassing-Aspirin-and-probiotic-Lactobacillus-fns-as-antimetastasis-agent-by-increasing-BIRC5-PDCD4-p53-TAp73-TAp63-and-others.jpg April 18, 2019 April 18, 2019

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that: An aspirin a day keeps metastatic cancer away, if so,…

April 2, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as PTPN14, SMARCA4, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 3/April/2019, 12.14 am

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as PTPN14, SMARCA4, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 3/April/2019, 12.14 am https://genomediscovery.org/wp-content/uploads/2019/04/A-pharmaceutical-mixture-encompassing-MND-and-the-probiotic-Lactobacillus-attenute-tumor-prog-through-induction-of-PTPN14-and-SMARCA4.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/04/A-pharmaceutical-mixture-encompassing-MND-and-the-probiotic-Lactobacillus-attenute-tumor-prog-through-induction-of-PTPN14-and-SMARCA4.jpg April 2, 2019 April 2, 2019

What we say: On the foundation of this interesting finding, Dr L Boominathan PhD, the Director-cum-chief Scientist of GBMD, reports that: Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in…

March 29, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as Sprouty1/2, hMSH2, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 29/March/2019, 10.34 pm

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing a pharmacological formulation encompassing Metformin, Navitoclax/ABT-263, & Dasatinib (MND) and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as Sprouty1/2, hMSH2, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 29/March/2019, 10.34 pm https://genomediscovery.org/wp-content/uploads/2019/03/A-pharmaceutical-mixture-encompassing-MND-and-or-the-probiotic-Lactobacillus-increase-the-exp-of-a-number-of-tum.-supp.-including-Sprouty1.2-and-hMSH2.jpg2_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/03/A-pharmaceutical-mixture-encompassing-MND-and-or-the-probiotic-Lactobacillus-increase-the-exp-of-a-number-of-tum.-supp.-including-Sprouty1.2-and-hMSH2.jpg2_.jpg March 29, 2019 March 29, 2019

March 3, 2019

Combinatorial therapy for attenuating prostate cancer bone metastasis: A pharmaceutical mixture encompassing Simvastatin and Navitoclax (SAN) inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via upregulation of its target gene, 3/March/2019, 8.33 am

Combinatorial therapy for attenuating prostate cancer bone metastasis: A pharmaceutical mixture encompassing Simvastatin and Navitoclax (SAN) inhibits the expression of Monoamine oxidase A (MAOA), inhibits Shh-IL6-RANKL signaling network, suppresses tumor-stromal interactions, reduces prostate cancer metastasis and prolongs survival via upregulation of its target gene, 3/March/2019, 8.33 am https://genomediscovery.org/wp-content/uploads/2019/02/A-therapeutic-mix-encompassing-Simvastatin-and-Navitoclax.ABT263-SAN-functions-as-an-anti-metastasis-agent-in-metastatic-cancers-by-decreasing-MAOA-expression.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/02/A-therapeutic-mix-encompassing-Simvastatin-and-Navitoclax.ABT263-SAN-functions-as-an-anti-metastasis-agent-in-metastatic-cancers-by-decreasing-MAOA-expression.jpg March 3, 2019 March 3, 2019

Introduction: What they say: A study from the Uro-Oncology Research Program, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, USA shows that “MAOA-Dependent Activation of Shh-IL6-RANKL Signaling Network Promotes…

February 24, 2019

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing Canthardin and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as TPM1, TIMP3, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 25/February/2019, `1.27 am

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced metastatic cancers: A pharmaceutical mixture encompassing Canthardin and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as TPM1, TIMP3, p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 25/February/2019, `1.27 am https://genomediscovery.org/wp-content/uploads/2019/02/Cantharidin-functions-as-an-anti-tumor.metastasis-agent-by-increasing-the-expression-of-tumor.metastasis-suppressors-including-TPM1-TIMP3-p53.21-TA-p73.p63-and-INK4a.ARF_.jpg 960 720 Dr Boomi's Genom-2-Discovery Center Dr Boomi's Genom-2-Discovery Center https://genomediscovery.org/wp-content/uploads/2019/02/Cantharidin-functions-as-an-anti-tumor.metastasis-agent-by-increasing-the-expression-of-tumor.metastasis-suppressors-including-TPM1-TIMP3-p53.21-TA-p73.p63-and-INK4a.ARF_.jpg February 24, 2019 February 24, 2019

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