Cancer

December 6, 2018

Probiotic-based chemotherapy for “awakening the sleeping/cancer-protecting angels” in mutant p53-expressing human tumors: A pharmaceutical composition encompassing Valsartan, a medication used in the treatment of high blood pressure and congestive heart failure, and Lactobacillus Rhamnosus increases the expression of tumor suppressors genes, such as PTPN14, p12DOC1, TA-p73/p63, p53 and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene , 6/December/2018, 3.24 pm

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
December 5, 2018

Probiotic-based therapy for Metastatic cancers: Probiotic Lactobacillus rhamnosus decreases the expression of metastasis promoters ZBTB2 and PPM1F, inhibits cell cycle progression, and suppresses migration, invasion, and metastasis of cancer cells, via up regulation of its target gene, 5/December/2018, 10.44 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
December 5, 2018

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced ovarian cancer and other metastatic cancers: A pharmaceutical mixture encompassing Olaparib, an FDA-approved poly (adenosine diphosphate-ribose) polymerase inhibitor, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as KIBRA, p57Kip2,   p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 5/December/2018, 2.29 pm

Introduction: What they say: A study from the Stephenson Cancer Center at the University of Oklahoma, Oklahoma City (K.M.); University of Milan-Bicocca, European Institute of Oncology […]
December 5, 2018

A probiotic-based therapy for Metastatic cancers: Probiotic Lactobacillus Rhamnosus decreases the expression of PPM22 and inhibits migration, invasion and metastasis of cancer cells via up-regulation of its target gene, 5/December/2017, 2.18 pm

From Significance of the study to Public health relevance: Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]