Cancer

Vitamin-based therapy for cancer metastasis: Riboflavin inhibits the expression of IL-6/8, decreases the experssion of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 27/July/2017, 10.36 pm
Vitamin-based therapy for cancer metastasis: Riboflavin inhibits the expression of IL-6/8, decreases the experssion of down stream molecules WASF3 and Arp2/3, suppresses tumor cell migration, reduces metastasis and prolongs survival via up regulation of its target gene, 27/July/2017, 10.36 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland 21218, USA; Johns Hopkins Physical Sciences-Oncology Center, The Johns Hopkins University,…

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Natural product-derived therapy for brain tumor and oesophageal squamous cell carcinoma:  Matrine, isolated from Sophora flavescens, inhibits the expression of Integrin a7 (ITGA7), impairs laminin-induced/FAK mediated signalling, inhibits the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 27/July/2017, 10.30 pm
Natural product-derived therapy for brain tumor and oesophageal squamous cell carcinoma:  Matrine, isolated from Sophora flavescens, inhibits the expression of Integrin a7 (ITGA7), impairs laminin-induced/FAK mediated signalling, inhibits the proliferation of glioblastoma and oesophageal squamous cell carcinoma stem cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 27/July/2017, 10.30 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Institute of General Pathology, Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli, 00168 Rome, Italy; Department of Oncology and…

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Natural product-derived Ptpn2 pathway blockade enhances the efficacy of Cancer immunotherapy: Artemisinin, isolated from Artemisia Annua L, inhibits the expression of protein tyrosine phosphatase PTPN2, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 27/July/2017, 1.00 pm
Natural product-derived Ptpn2 pathway blockade enhances the efficacy of Cancer immunotherapy: Artemisinin, isolated from Artemisia Annua L, inhibits the expression of protein tyrosine phosphatase PTPN2, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 27/July/2017, 1.00 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142,…

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Molecular therapy for glioblastoma: MiRNA-340  inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 27/July/2017,  12.54 am
Molecular therapy for glioblastoma: MiRNA-340  inhibits the expression of JMJD6, impairs functioning of transcription elongation machinery, inhibits the proliferation of glioblastoma cells, suppresses tumor cell migration, reduces metastasis and prolongs survival via down regulation of its target gene, 27/July/2017,  12.54 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Department of Stem Cell Biology and Regenerative Medicine, Lerner Research Institute, Ohio, USA shows that “Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.” This…

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 Natural product-derived therapy for prostate cancer: Magnolol, one of the components of Magnolol Grandiflora (MG), inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regulation of its target gene, 26/July/2017, 11.44 pm
 Natural product-derived therapy for prostate cancer: Magnolol, one of the components of Magnolol Grandiflora (MG), inhibits the expression of mTORC1 and its downstream target AMD1, dismantles mTORC1-AMD1 signaling network, decreases polyamine levels, and inhibits prostate cancer progression via up regulation of its target gene, 26/July/2017, 11.44 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from CIC bioGUNE (Center for Cooperative Research in Biosciences), Bizkaia Technology Park, 801 Building, 48160 Derio, Spain shows that “mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer.” This…

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Natural product-derived Ptpn2 pathway blockade enhances the efficacy of Cancer immunotherapy: Honokiol, isolated from Magnolia grandiflora, inhibits the expression of protein tyrosine phosphatase PTPN2, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 25/July/2017, 2.23 pm
Natural product-derived Ptpn2 pathway blockade enhances the efficacy of Cancer immunotherapy: Honokiol, isolated from Magnolia grandiflora, inhibits the expression of protein tyrosine phosphatase PTPN2, increases interferon-IFNγ signalling, augments antigen presentation and unfolding response, increases Cytotoxic activity of T-cells, decreases tumor burden and increases survival via up-regulation of its target gene, 25/July/2017, 2.23 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction:What they say: A recent study from Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA; Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142,…

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