Cardiac regeneration

January 10, 2020

Marine bacteria aids in heart regeneration and promotes stress resistance: Maritoclax (Marinopyrorle A), found in Marine bacteria, promotes heart regeneration and function and augments stress resistance against hypoxic stress through down regulation of p38-α, 10/January/2020, 7.01 am

Idea Proposed/Formulated by: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD. From research findings to Therapeutic opportunity: This study suggests, for the first time, that Maritoclax (Marinopyrorle A), […]
January 8, 2020

Meformin aids in heart regeneration and promotes stress resistance: Metformin, the widely used drug in the treatment of T2DM, promotes heart regeneration and function and augments stress resistance against hypoxic stress through down regulation of p38-α, 8/January/2020, 1.58 pm

Idea Proposed/Formulated by: Dr L Boominathan Ph.D. Significance: A number of studies suggest that Metformin, the widely used drug in the treatment of T2DM, protects against cardaic […]
December 31, 2019

Little RNA can protect against cardiac dysfunction: LncRNA NEAT1-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: LncRNA NEAT1 (Nuclear Enriched Abundant Transcript 1 (NEAT1) increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, 31/December/2019, 11.41 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
December 24, 2019

Ascorbic acid-based regenerative cardiovascular therapy: Molecular mechanistic insight into how Vitamin C/Ascorbic acid protects against and promotes functional recovery after Myocardial Infarction:  Vitamin C/Ascorbic acid(AA)  inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte proliferation, regeneration and survival after myocardial infarction, via up-regulation of its target gene, 24/December/2019, 11.55 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]