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Diabetes

August 10, 2018

I do more than what I intended for: Estrogen comes to the rescue of blood sugar disease: Estrogen, a female sex steroid hormone,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 10/August/2018, 9.59 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
August 8, 2018

Estrogen-based therapy for body weight control, energy homeostasis and TIIDM: Estradiol (E2) decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 8/August/2018, 9.48 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
August 4, 2018

Reproductive hormone aids in control of body weight, energy homeostasis and TIIDM: Human chorionic gonadotrophin (hCG), normally used as a marker for pregnancy, decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 4/August/2017, 12.30 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
August 4, 2018

Unknown function of the known reproductive hormone Progesterone (P4): Progesterone (P4), an endogenous steroid hormone, may aid in the treatment of TIIDM and obesity-associated metabolic deficits: Progesterone (P4) activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 4/August/2018, 10.53 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]