Diabetes

Mechanistic insights into how Ciliary neurotrophic factor (CNTF) aids in control of body weight, energy homeostasis and TIIDM:  CNTF increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 20/June/2019, 10.52 pm
Mechanistic insights into how Ciliary neurotrophic factor (CNTF) aids in control of body weight, energy homeostasis and TIIDM:  CNTF increases REV-ERB and its down stream target genes, inhibits lipid accumulation, improves dyslipidemia and insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 20/June/2019, 10.52 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida 33458, USA shows that “Regulation of circadian behaviour and metabolism by synthetic…

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Mechanistic insights into how Liraglutide aids in remission of Diabetes: Liraglutide (brand name: Victoza, Saxenda and others), a  drug used in the treatment of type II diabetes, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia, via downregulation of  Sox4 and its target gene Amysin,  20/June/2019, 7.13 am
Mechanistic insights into how Liraglutide aids in remission of Diabetes: Liraglutide (brand name: Victoza, Saxenda and others), a  drug used in the treatment of type II diabetes, inhibits Amysin expression, increases insulin secretion, and decreases the risk of hyperglycemia, via downregulation of  Sox4 and its target gene Amysin,  20/June/2019, 7.13 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  Nobel laureate [ in Physiology/Medicine in 1975] Prof. David Baltimore and his research team, from California Institute of Technology, California, USA, had reported in the September 14, 2014 issue of the Journal “Journal…

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A coconut way to say no to weight gain and Diabetes: Coconut oil-derived compound Lauric acid plays a significant role in body weight control, energy homeostasis and TIIDM: Lauric acid (LA-C12) or Dodecanoic acid (DA), one of the main components (48-52%) of coconut oil,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/June/2019, 11.14 pm
A coconut way to say no to weight gain and Diabetes: Coconut oil-derived compound Lauric acid plays a significant role in body weight control, energy homeostasis and TIIDM: Lauric acid (LA-C12) or Dodecanoic acid (DA), one of the main components (48-52%) of coconut oil,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/June/2019, 11.14 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule…

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Curing diabetes with Liraglutide: Liraglutide-based therapy for TIIDM and obesity-associated metabolic deficits: Liraglutide (trade name:Victoza, Saxenda), a glucagon-like peptide-1 agonist used in the treatment of diabetes, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, decreases TXNIP expression, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 04/June/2019, 12.14 pm
Curing diabetes with Liraglutide: Liraglutide-based therapy for TIIDM and obesity-associated metabolic deficits: Liraglutide (trade name:Victoza, Saxenda), a glucagon-like peptide-1 agonist used in the treatment of diabetes, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, decreases TXNIP expression, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 04/June/2019, 12.14 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite by…

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Curing diabetes with commonly available blood pressure drug Verapamil: Verapamil-based therapy for TIIDM and obesity-associated metabolic deficits: Verapamil  (trade name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina and others, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, decreases TXNIP expression, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 04/June/2019, 7.48 am
Curing diabetes with commonly available blood pressure drug Verapamil: Verapamil-based therapy for TIIDM and obesity-associated metabolic deficits: Verapamil  (trade name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina and others, increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, decreases TXNIP expression, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 04/June/2019, 7.48 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent suppression of appetite by…

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Chronic isolation stress promotes the development of type II diabetes mellitus and cardiovascular dysfunction: Chronic isolation stress decreases the expression of IGF1R, INSR, and IRS2, and inhibits insulin-sensitized state, via down-regulation of  its target gene Lin28, 1/June/2019, 5.55 pm
Chronic isolation stress promotes the development of type II diabetes mellitus and cardiovascular dysfunction: Chronic isolation stress decreases the expression of IGF1R, INSR, and IRS2, and inhibits insulin-sensitized state, via down-regulation of  its target gene Lin28, 1/June/2019, 5.55 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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