Diabetes

Mechanistic insights into how social isolation stress promotes weight gain and Diabetes: Social isolation stress increases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, aggravates insulin resistance, decreases energy utilization, promotes weight gain and diet-induced obesity and TIIDM, via up regulation of its target gene, 30/May/2019, 6.58 am
Mechanistic insights into how social isolation stress promotes weight gain and Diabetes: Social isolation stress increases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, aggravates insulin resistance, decreases energy utilization, promotes weight gain and diet-induced obesity and TIIDM, via up regulation of its target gene, 30/May/2019, 6.58 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule…

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Combinatorial therapy for autoimmune diabetes (TIDM):  A pharmaceutical mixture encompassing Prostaglandin E2 (PGE2) and Ethyl Pyruvate (EP) [PGE2EP]  increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 24/Mat/2019, 11.01 pm
Combinatorial therapy for autoimmune diabetes (TIDM):  A pharmaceutical mixture encompassing Prostaglandin E2 (PGE2) and Ethyl Pyruvate (EP) [PGE2EP]  increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 24/Mat/2019, 11.01 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical Sciences, University of…

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A commonly prescribed blood-pressure drug comes to the rescue of diabetes (TIIDM): Verapamil (brand name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina, supraventricular tachycardia, migraines, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/May/2019, 10.31 pm
A commonly prescribed blood-pressure drug comes to the rescue of diabetes (TIIDM): Verapamil (brand name: Calan, Isoptin, and others), a calcium channel blocker used in the treatment of high blood pressure, angina, supraventricular tachycardia, migraines, increases Pax6 and insulin expression, decreases the levels of glucagon, ghrelin and Somatostatin, reduces metabolic stress, improves insulin sensitivity, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/May/2019, 10.31 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Developmental Biology and Cancer Research, The Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, Jerusalem, Israel shows that…

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Blood pressure drug Verapamil comes to the rescue of blood sugar disease: Verapamil (brand name: Calan, Isoptin and others), a calcium channel blocker that aids in the treatment of high blood pressure, angina pectoris, supraventricular tachyarrhythmias and others,   inhibitor used in the treatment of hyperglycemia,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 17/May/2019, 10.40 pm
Blood pressure drug Verapamil comes to the rescue of blood sugar disease: Verapamil (brand name: Calan, Isoptin and others), a calcium channel blocker that aids in the treatment of high blood pressure, angina pectoris, supraventricular tachyarrhythmias and others,   inhibitor used in the treatment of hyperglycemia,  increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 17/May/2019, 10.40 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Revealing the anti-diabetic agent in the known anti-cancer agent Bexarotene: Bexarotene-based therapy for body weight control, energy homeostasis and TIIDM:Bexarotene inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 10/May/2019, 6.44 am
Revealing the anti-diabetic agent in the known anti-cancer agent Bexarotene: Bexarotene-based therapy for body weight control, energy homeostasis and TIIDM:Bexarotene inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 10/May/2019, 6.44 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Reversing Diabetes with blood pressure drug Verapamil: Verapamil [brand name: (Calan, Isoptin, Verelan)], a calcium channel blocker, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 8/May/2019, 8.19 am
Reversing Diabetes with blood pressure drug Verapamil: Verapamil [brand name: (Calan, Isoptin, Verelan)], a calcium channel blocker, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 8/May/2019, 8.19 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, Birmingham, AL shows that…

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