Diabetes

August 4, 2018

Reproductive hormone aids in control of body weight, energy homeostasis and TIIDM: Human chorionic gonadotrophin (hCG), normally used as a marker for pregnancy, decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 4/August/2017, 12.30 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
August 4, 2018

Unknown function of the known reproductive hormone Progesterone (P4): Progesterone (P4), an endogenous steroid hormone, may aid in the treatment of TIIDM and obesity-associated metabolic deficits: Progesterone (P4) activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM, via down-regulation of its target gene, 4/August/2018, 10.53 am

Introduction: What they say A study from the Department of Physiology-Cellular Biophysics, College of Physicians and Surgeons, Columbia University, New York, New York, USA shows that “MC4R-dependent […]
August 1, 2018

Repurposing the H.Pylori vaccine CTB-UE into an anti-diabetic vaccine:  CTB-UE vaccine-based therapy for body weight control, energy homeostasis and TIIDM:CTB-UE vaccine, protects against infections caused by H.Pylori, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 1/August/2018, 3.34 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
August 1, 2018

Reproductive hormone aids in the treatment of blood sugar disease: FSH (Follicle stimulating hormone)-based therapy for DM: FSH increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state, via up-regulation of  its target gene Lin28, 1/August/2018, 10.59 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]