Diabetes

Molecular therapy for body weight control, energy homeostasis and TIIDM: Lactulose (Brand names: Cholac, Generlac, Consulose, Duphalac), a non-absorbable sugar that aids in the treatment of constipation and hepatic encephalopathy,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2017, 9.10 am
Molecular therapy for body weight control, energy homeostasis and TIIDM: Lactulose (Brand names: Cholac, Generlac, Consulose, Duphalac), a non-absorbable sugar that aids in the treatment of constipation and hepatic encephalopathy,  decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2017, 9.10 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Polyamine-based therapy for diabetes (TIDM): Spermidine, a natural polyamine, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2018, 8.47 am
Polyamine-based therapy for diabetes (TIDM): Spermidine, a natural polyamine, increases GLP1R and Caveolin-1 (CAV-1) expression, promotes glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 3/March/2018, 8.47 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say   A study from the Comprehensive Diabetes Center and Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Alabama at Birmingham, Birmingham, AL shows that…

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Molecular therapy for body weight control, energy homeostasis and TIIDM: Spermidine, an endogenous polyamine, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/March/2018, 7.17 am
Molecular therapy for body weight control, energy homeostasis and TIIDM: Spermidine, an endogenous polyamine, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/March/2018, 7.17 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Molecular therapy for TIIDM and Metabolic defects: Syringic acid increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 28/November/2017, 11.43 pm
Molecular therapy for TIIDM and Metabolic defects: Syringic acid increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 28/November/2017, 11.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma ideas posted today (28/February/2018) will be…

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Amino acid-based therapy for TIIDM and obesity-associated metabolic deficits: D-Serine increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 28/February/2018, 11.32 pm
Amino acid-based therapy for TIIDM and obesity-associated metabolic deficits: D-Serine increases Lipocalin 2 (LCN2) expression, activates an MC4R-dependent anorexigenic pathway, suppresses appetite and weight gain, increases insulin secretion, improves glucose tolerance, promotes glucose homeostasis, improves obesity-associated metabolic deficits and prevents progression to TIIDM via down regulation of its target gene, 28/February/2018, 11.32 pm 960 720 Dr Boomi's Genom-2-Discovery Center

National Science day special ********* We wish everyone a very happy national science day. On this special occasion, we are happy to announce that Bio-Med/Pharma ideas posted today (28/February/2018) will be…

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Amino sugar-based therapy for reversing TIIDM:  D-Glucosamine augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 27/February/2017, 1.10 pm
Amino sugar-based therapy for reversing TIIDM:  D-Glucosamine augments the expression of FGF19 and FGF1,   attenuates hepatic glucose production, decreases hepatic acetyl CoA content, brings down the levels of plasma ACTH, and corticosterone, augments insulin sensitivity, promotes weight loss and alleviates TIIDM via up regulation of its target gene, 27/February/2017, 1.10 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say  A study from Diabetes and Obesity Center of Excellence, Department of Medicine, University of Washington, Seattle, Washington, USA shows that Central injection of FGF1 induces sustained…

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