Diabetes

Vitamin-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Pyridoxamine (PM), a form of Vitamin-B6, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 14/December/2017, 1.22 am
Vitamin-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Pyridoxamine (PM), a form of Vitamin-B6, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 14/December/2017, 1.22 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis regulates glucose metabolism.” This study…

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Vitamin-based therapy for body weight control, energy homeostasis and TIIDM:  A therapeutic mix encompassing  Vitamin-B12 and Omega-3 fatty acids decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 14/December/2017, 12.55 am
Vitamin-based therapy for body weight control, energy homeostasis and TIIDM:  A therapeutic mix encompassing  Vitamin-B12 and Omega-3 fatty acids decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 14/December/2017, 12.55 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Natural product-based therapy for Diabetic retinopathy: Sulforaphane, isolated from Broccoli, among others, inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 12/December/2017, 12.07 am
Natural product-based therapy for Diabetic retinopathy: Sulforaphane, isolated from Broccoli, among others, inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 12/December/2017, 12.07 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Molecular therapy for body weight control, energy homeostasis and TIIDM: Glimepiride (Brand name: Amaryl), an anti-hyperglycemic medication,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 11/December/2017, 10.41 pm
Molecular therapy for body weight control, energy homeostasis and TIIDM: Glimepiride (Brand name: Amaryl), an anti-hyperglycemic medication,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 11/December/2017, 10.41 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Combinatorial therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture encompassing Trimetazidine (TMZ) and Astaxanthin (ATX) [TMZATX]  increases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 11/December/2017, 10.32 pm
Combinatorial therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture encompassing Trimetazidine (TMZ) and Astaxanthin (ATX) [TMZATX]  increases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 11/December/2017, 10.32 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.” This research paper…

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Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Carvedilol[Trade name: Coreg], Nonselective beta/alpha1 blocker used in the treatment of myocardial dysfunction and hypertension, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/December/2017, 9.59 am
Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Carvedilol[Trade name: Coreg], Nonselective beta/alpha1 blocker used in the treatment of myocardial dysfunction and hypertension, inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 10/December/2017, 9.59 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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