Diabetes

Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Glabridin, an isoflavane isolated from Licorice (Glycyrrhiza glabra),  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/December/2017, 6.14 am

Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Glabridin, an isoflavane isolated from Licorice (Glycyrrhiza glabra),  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 2/December/2017, 6.14 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Formononetin, isolated from Trifolium pratense,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 30/November/2017, 11.49 pm

Natural product-based therapy for body weight control, energy homeostasis and TIIDM: Formononetin, isolated from Trifolium pratense,  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 30/November/2017, 11.49 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Regenerative therapy for reversing and/or attenuating diabetes: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 30/November/2017, 10.43 pm

Regenerative therapy for reversing and/or attenuating diabetes: Cilostazol, a phosphodiesterase inhibitor used in the treatment of Peripheral vascular disease, decreases mTOR expression, promotes regeneration of insulin-producing ß cells, increases insulin secretion, promotes glucose homeostasis and reverses T1D and T2D via down regulation of its target gene, 30/November/2017, 10.43 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Longevity Institute, School of Gerontology, Department of Biological Sciences, University of Southern California, 3715 McClintock Avenue, Los Angeles, California, USA; and Koch Institute…

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Molecular therapy for TIIDM and Metabolic defects: Cilostazol, an inhibitor of phosphodiesterase 3B, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/November/2017, 11.56 pm

Molecular therapy for TIIDM and Metabolic defects: Cilostazol, an inhibitor of phosphodiesterase 3B, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 29/November/2017, 11.56 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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Natural product therapy for body weight control, energy homeostasis and TIIDM:  Resveratrol, isolated from Polygonum Cuspidatum, grapes, ground nuts, among others,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 25/November/2017, 4.06 pm

Natural product therapy for body weight control, energy homeostasis and TIIDM:  Resveratrol, isolated from Polygonum Cuspidatum, grapes, ground nuts, among others,  decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 25/November/2017, 4.06 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Lifespan extension therapy:Tesaglitazar (AZ242), an insulin sensitizer,  may increase life span via up-regulation of its target gene BubR1, 19/October/2017, 11.14 pm

Lifespan extension therapy:Tesaglitazar (AZ242), an insulin sensitizer,  may increase life span via up-regulation of its target gene BubR1, 19/October/2017, 11.14 pm 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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