Diabetes

December 23, 2018

Molecular therapy for Cardiomyopathy: Metoprolol (brand name:lopressor), used to treat high blood pressure and angina, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via upregulation of its target gene, 23/December/2018,  11.04 pm

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
December 20, 2018

Valproic acid-based therapy for TIIDM and Metabolic defects: Valproic acid (brand names: Convulex, Depakote, epilim, stavzor and others), a drug used to treat seizures/epilepsy, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 20/December/2018, 11.23 pm

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]
December 20, 2018

Molecular therapy for body weight control, energy homeostasis and TIIDM: AP-1 (Activator protein-1) inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up-regulation of its target gene, 20/December/2018, 10.59pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
December 20, 2018

Hot water immersion therapy for TIIDM and Metabolic defects: Hot water immersion (at 39C for 1 hour) therapy increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 20/December/2018, 10.45 pm

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC […]