Heart attack

January 12, 2019

Ribonucleic acid-based therapy for Myocardial Infarction: LncRNA ADAM12 inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 12/January/2019, 7.40 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]
January 11, 2019

Ribonucleic acid-based therapy for cardiac hypertrophy and fibrosis: LncRNA XIST decreases MiR-29 expression, activates Wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via upregulation of its target gene, 11/January/2019, 11.58 pm

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]
January 11, 2019

Mesenchymal stem cell-based therapy for Cardiomyopathy: Mesenchymal stem cells (MSCs) decrease the expression of Sox6, restore the balance between slow- and fast-twitch myofiber proteins and alleviate Cardiomyopathy, via upregulation of its target gene, 11/January/2019,  11.07 pm

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
January 11, 2019

Molecular therapy for heart regeneration and repair:  Metoprolol (trade name: Lopressor), used to treat high blood pressure and heart pain, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 11/January/2017, 10.24 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]