Heart attack

August 17, 2018

A Relaxin(g)-way to say no to cardiac diseases: Relaxin-based therapy for attenuating pathogenesis-associated with Myocardial infarction: Relaxin, a reproductive hormone,  decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 18/August/2018, 1.11 am

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
August 17, 2018

Relax (in) your way to say no to myocardial diseases: Relaxin-based therapy for cardiac repair and myocardial infarction: Relaxin, a reprodutive hormone,  increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 17/August/2018, 11.59 pm

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
August 4, 2018

Revealing the unrevealed function of  the reproductive hormone Follicle-stimulating hormone (FSH) in the heart: FSH,  a gonadotropin, and glycoprotein polypeptide hormone, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of PNUTS, 4/August/2018, 9.50 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of the […]
August 3, 2018

Optimal levels of a reproductive hormone FSH(Follicle stimulating hormone) may keep cardiac diseases at bay: FSH-based cardiac rejuvenation therapy: FSH, a gonadotrophin and polypeptide hormone, suppresses tumor suppressor INK4a/p16 expression and inhibits dilated cardiomyopathy, via upregulation of its target gene, 3/August/2018, 1.25 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Optimal levels of a reproductive hormone FSH(Follicle stimulating hormone) may keep cardiac diseases at bay: […]