Heart attack

April 9, 2019

Carvedilol-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients: Carvedilol (Brand name: Coreg), a non-selective beta blocker used to treat congestive heart failure, increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via up-regulation of its target gene, , 9/April/2019, 11.17 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
April 8, 2019

Mechanistic insights into why consumption of high fact diet is bad for your heart: High fat diet promotes DNA damage responses, decreases telomerase expression, accelerates telomere shortening, and decreases cardiomyocyte survival after myocardial infarction, via downregulation of PNUTS, 8/April/2019, 11.38 pm

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac aging and function.” This study was published, in the 7 March  2013 issue of the […]
March 31, 2019

Intracardiac injection of Erythropoietin/Hematopoietin attenuates pathogenesis-associated with Myocardial infarction: Erythropoietin/Hematopoietin decreases IRF3, GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leukocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up regulation of its target gene, 31/March/2019, 9.29 am

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
March 31, 2019

Intracardiac/epicardial injection of Cyclic Helix-B peptide (CHBP) protects against and promotes functional recovery after Myocardial Infarction:  CHBP, derived from erythropoietin/hematopoietin, inhibits DNA damage responses, induces telomerase expression, inhibits telomere shortening, and promotes cardiomyocyte survival after myocardial infarction, via up-regulation of its target gene, 31/March/2019, 9.02 am

What they say:  A recent study from the Institute for Cardiovascular Regeneration, Centre of Molecular Medicine, Frankfurt, Germany shows that “MicroRNA-34a regulates cardiac ageing and function.” This study was published, in the 7 March  2013 issue of of […]