Ideas

Probiotic-based Life-extension therapy: Probiotic lactobacillus reuteri  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 25/December/2018, 10.26 pm
Probiotic-based Life-extension therapy: Probiotic lactobacillus reuteri  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 25/December/2018, 10.26 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Life-extension therapy: Troglitazone (brand name: Rezulin, Resulin, Romozin, Noscal), an anti-diabetic and anti-inflammatory drug,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 25/December/2018, 5.55 pm
Life-extension therapy: Troglitazone (brand name: Rezulin, Resulin, Romozin, Noscal), an anti-diabetic and anti-inflammatory drug,  inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span, 25/December/2018, 5.55 pm 960 720 Dr Boomi's Genom-2-Discovery Center

What they say: A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal protein S6 kinase 1…

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Molecular therapy for heart regeneration and repair: Carvidiol (trade name: Coreg), used to treat congestive heart failure and high blood pressure, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 24/December/2017, 10.38 am
Molecular therapy for heart regeneration and repair: Carvidiol (trade name: Coreg), used to treat congestive heart failure and high blood pressure, increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 24/December/2017, 10.38 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, Durham, North Carolina 27708,…

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Molecular therapy for TIIDM and Metabolic defects: Carvedilol (brand name: Coreg), used to treat high blood pressure and congestive heart failure, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/December/2018, 11.19 pm
Molecular therapy for TIIDM and Metabolic defects: Carvedilol (brand name: Coreg), used to treat high blood pressure and congestive heart failure, increases Sirtuin-4 expression, augments insulin secretion, reduces metabolic stress, improves glucose uptake, promotes glucose homeostasis and prevents progression to TIIDM via down regulation of its target gene, 23/December/2018, 11.19 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the “Duke Molecular Physiology Institute and Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, NC 27701, USA; Department of…

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Molecular therapy for Cardiomyopathy: Metoprolol (brand name:lopressor), used to treat high blood pressure and angina, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via upregulation of its target gene, 23/December/2018,  11.04 pm
Molecular therapy for Cardiomyopathy: Metoprolol (brand name:lopressor), used to treat high blood pressure and angina, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy via upregulation of its target gene, 23/December/2018,  11.04 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart function through microRNA-mediated Sox6 repression.” This…

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Mechanistic insights into how Carvedilol may aid in attenuating pathogenesis-associated with Myocardial infarction: Carvedilol (brand name: Coreg),  used in the treatment of high blood pressure and congestive heart failure, decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 23/December/2018, 5.47 pm
Mechanistic insights into how Carvedilol may aid in attenuating pathogenesis-associated with Myocardial infarction: Carvedilol (brand name: Coreg),  used in the treatment of high blood pressure and congestive heart failure, decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 23/December/2018, 5.47 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston,…

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