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Ideas

December 2, 2018

A probiotic way to stay free of cardiac diseases: Lactobacillus fermentum -based therapy for attenuating pathogenesis-associated with Myocardial infarction: Lactobacillus fermentum NCIMB 5221 decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 2/December/2018, 11.11 pm

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and […]
December 2, 2018

Probiotic-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:   Probiotic Lactobacillus fermentum ZYL0401 increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via down-regulation of its target gene, 2/December/2018, 10.29 pm

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was […]
December 1, 2018

Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 2/December/2018, 12.15 am

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 […]
December 1, 2018

Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced ovarian cancer and other metastatic cancers: A pharmaceutical mixture encompassing Olaparib, an FDA-approved poly (adenosine diphosphate-ribose) polymerase inhibitor, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as GRHL3, BIRC5,   p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 2/December/2018, 12.08 am

Introduction: What they say: A study from the Stephenson Cancer Center at the University of Oklahoma, Oklahoma City (K.M.); University of Milan-Bicocca, European Institute of Oncology […]
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