Ideas

A probiotic-based immune enhancement therapy: Probiotic Lactobacillus Brevis increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 5/December/2018, 2.02 pm
A probiotic-based immune enhancement therapy: Probiotic Lactobacillus Brevis increases SOX2 expression, and promotes innate immunity against bacterial infection, via down-regulation of its target gene, 5/December/2018, 2.02 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say:   A recent study from the Institute of Biophysics, Chinese Academy of Sciences, Beijing, China shows that “Sox2 functions as a sequence-specific DNA sensor in neutrophils to initiate innate…

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Hot water immersion-based adjuvant therapy for aging-associated diseases and Lifespan extension: Hot water immersion (at 39C for 1 hour) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 3/November/2018, 11.45 pm
Hot water immersion-based adjuvant therapy for aging-associated diseases and Lifespan extension: Hot water immersion (at 39C for 1 hour) increases NMN/NAD levels, decreases interaction of DBC1 with PARP1, increases PARP1 activity, promotes DNA repair, augments tolerance against radiation, cancer and aging, via down-regulation of its target gene, 3/November/2018, 11.45 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Department of Genetics, Paul F. Glenn Center for the Biology of Aging, Harvard Medical School, Boston, MA, USA; and Department of Pharmacology, School…

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A probiotic way to stay free of cardiac diseases: Lactobacillus fermentum -based therapy for attenuating pathogenesis-associated with Myocardial infarction: Lactobacillus fermentum NCIMB 5221 decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 2/December/2018, 11.11 pm
A probiotic way to stay free of cardiac diseases: Lactobacillus fermentum -based therapy for attenuating pathogenesis-associated with Myocardial infarction: Lactobacillus fermentum NCIMB 5221 decreases IRF3 (Interferon regulatory transcription factor-3), GM-CSF (Granulocyte-macrophage colony-stimulating factor) and GRK2(G protein-coupled receptor kinase) expression, inhibits undue leucocyte activation and invasion, suppresses recruitment of inflammatory cells, inhibits ventricular dilation, and promotes heart repair and survival, via up-regulation of its target gene, 2/December/2018, 11.11 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A recent study from Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA; and Cardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston,…

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Probiotic-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:   Probiotic Lactobacillus fermentum ZYL0401 increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via down-regulation of its target gene, 2/December/2018, 10.29 pm
Probiotic-based Regenerative therapy for regaining the lost cardiomyocytes in Myocardial patients:   Probiotic Lactobacillus fermentum ZYL0401 increases the expression of ERBB2/Her2 and promotes dedifferentiation  of cardiomyocytes, via down-regulation of its target gene, 2/December/2018, 10.29 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from the Department of Biological Regulation, Weizmann Institute of Science, Rehovot 76100, Israel shows that “ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation.” This study was published, in the 6 April…

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Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 2/December/2018, 12.15 am
Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation of HIV-1 Gag protein, disrupts HIV-1 budding, and restricts HIV-1 production, via upregulation of its target gene, 2/December/2018, 12.15 am 960 720 Dr Boomi's Genom-2-Discovery Center

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that: Probiotics function as anti-HIV agents: Probiotic Lactobacillus casei strain shirota (LcS) increases Heme oxygenase 2 (HO-2) expression, blocks N-myristoylation…

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Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced ovarian cancer and other metastatic cancers: A pharmaceutical mixture encompassing Olaparib, an FDA-approved poly (adenosine diphosphate-ribose) polymerase inhibitor, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as GRHL3, BIRC5,   p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 2/December/2018, 12.08 am
Probiotic-based chemotherapy targeting cancer stem cells and immune-inhibitory receptors in advanced ovarian cancer and other metastatic cancers: A pharmaceutical mixture encompassing Olaparib, an FDA-approved poly (adenosine diphosphate-ribose) polymerase inhibitor, and probiotic Lactobacillus rhamnosus increases the expression of tumor suppressor genes, such as GRHL3, BIRC5,   p53, and TA-p73/p63, inhibits immune-inhibitory receptors/molecules, targets ovarian cancer stem cells, confers protection against chemoresistance and prolongs survival, via up-regulation of its target gene, 2/December/2018, 12.08 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say: A study from the Stephenson Cancer Center at the University of Oklahoma, Oklahoma City (K.M.); University of Milan-Bicocca, European Institute of Oncology Istituto di Ricovero e…

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