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Ideas

June 16, 2018

Natural product-derived therapy for cardiac hypertrophy and fibrosis: A pharmaceutical mixture encompassing βCryptoxanthin, Mangiferin & Glycyrrhetinic acid (CMG) decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via up regulation of its target gene, 16/June/2017, 7.07 pm

Introduction: What they say: A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]
June 14, 2018

Carbon monoxide-based therapy for body weight control, energy homeostasis and TIIDM: COR-M2( CO releasing molecule-2 )inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 14/June/2018, 11.18 pm

Introduction: What they say  A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator […]
June 14, 2018

Lifespan extension therapy: Epidermal growth factor (EGF) may increase life span via up-regulation of its target gene BubR1, 14/June/2018, 11.08 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
June 13, 2018

Carbon monoxide-based therapy for autoimmune diabetes (TIDM): Carbon monoxide (CO) releasing molecules-2 (COR-M2) increases the expression of PD-L1, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 13/June/2018, 9.23 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]
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