Ideas

August 23, 2018
Published by admin_auro at August 23, 2018
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Reproductive hormone protects against cardiac diseases: Relaxin-based therapy for Cardiomyopathy:  Relaxin, a protein hormone that facilitates labor and relaxes the uterine musculature, decreases the expression of Sox6, restores the balance between slow- and fast-twitch myofiber proteins and alleviates Cardiomyopathy, via up-regulation of its target gene, 23/August/2018, 2.54 pm

Introduction: What they say   A study from the Department of Cardiology, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, USA; and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, USA shows that “Trbp regulates heart […]
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August 23, 2018
Published by admin_auro at August 23, 2018
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A Lotus way to lengthen lifespan: The Lotus component Nucinferin-based therapy for life-span extension: Nucinferin, isolated from lotus leaf, may  increase insulin sensitivity, slow down cardiac aging, and increase lifespan, via up-regulation of BubR1 and others genes, 23/August/2018, 2.36 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston, USA; […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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Awakening the sleeping/cancer-protecting angels in mutant p53-expressing human tumors: PCGF2/Mel-18 increases the expression of tumor suppressors genes, such as  HNF4α, CADM2, p53, TAp63, TAp73, INK4a/ARF, and others, induces regression of p53-mutated human tumors, via down-regulation of its target gene, 22/August/2018, 7.48 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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August 22, 2018
Published by admin_auro at August 22, 2018
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Combinatorial  therapy for human cancers: A pharmaceutical mixture encompassing Metformin, Berberine, Despiramine, 17-AAG, Curcumin, Calcitriol, Capsaicin, Camptothecin, Simvastatin, Salinomycin, (MBDAAGCCCSS) inhibits the expression of KAT6A and KAT6B, increases the expression of INK4a/ARF and other genes, promotes senescence, prevents cancer recurrence, and prolongs survival, via up-regulation of its target gene, 22/August/2018, 7.35  am

Introduction: What they say: A study from the Medicinal Chemistry Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; The Walter and Eliza Hall […]
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