Ideas

June 3, 2018
Published by admin_auro at June 3, 2018
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Combinatorial therapy for Deafness: A therapeutic mix encompassing Brmocriptine, Cholecalciferol, Ajoene and DIM (BCAD)  increases the expression of ATG5 (Autophagy-related 5), prevents aggregation of proteins in inclusion bodies, inhibits hair cell degeneration,  improves hearing loss via up regulation of its target genes, 3/June/2018, 11.25 pm

What we say: Dr L Boominathan PhD, Director-cum-chief Scientist of GBMD, reports that:  Combinatorial therapy for Deafness: A therapeutic mix encompassing Brmocriptine, Cholecalciferol, Ajoene and DIM (BCAD)  increases the […]
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June 3, 2018
Published by admin_auro at June 3, 2018
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A ceramide way to treat Non-alcoholic fatty liver disease (NAFLD): α-galactosylceramide promotes degradation of HMGCR, decreases the levels of triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD via down regulation of its target gene, 3/June/2018, 11.18 pm

Significance of the study: Given that: (1)  15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]
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June 3, 2018
Published by admin_auro at June 3, 2018
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Interleukin-based therapy for body weight control, energy homeostasis and TIIDM: Interleukin-15 (IL-15) decreases CADM1 and its downstream target genes that inhibit glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 3/June/2017, 11.08 pm

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by […]
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June 3, 2018
Published by admin_auro at June 3, 2018
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Lifespan- and healthspan-extension therapy: Snai1/Snail, a protein that promotes epithelial to mesenchymal transition, may increase life span via up-regulation of its target gene BubR1 and others, 3/June/2018, 11.00 pm

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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