Ideas

March 17, 2018
Published by admin_auro at March 17, 2018
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A candy way to treat blood sugar disease: Sugar-based therapy for autoimmune diabetes (TIDM): D-Mannose, a C-2 epimer of glucose, increases PD-L1 expression, increases Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 17/March/2018, 8.28 am

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and […]
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March 17, 2018
Published by admin_auro at March 17, 2018
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Sugar-based therapy for Metastatic cancers: Xylobiose, a disaccharide of xylose, increases the expression of tumor/metastatic suppressors BTG2 and INK4a, inhibits cell cycle progression, and suppresses migration, invasion and metastasis of cancer cells via up regulation of its target gene, 17/March/2018, 7.23 am

From Significance of the study to Public health relevance:  Given that: (i) each year nearly 14 million people are diagnosed with cancer globally, and little more […]
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March 17, 2018
Published by admin_auro at March 17, 2018
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A sweet way to extend lifespan: Sugar-based Lifespan extension therapy: D-Allose, an aldohexose sugar and C-3 epimer of glucose, may increase life span via up-regulation of its target gene BubR1, 17/March/2018, 7.07 am

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]
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March 17, 2018
Published by admin_auro at March 17, 2018
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Natural product-based therapy for Regenerating the lost pancreatic β-cells in Diabetic patients: Spermidine, a natural polyamine, increases the expression of IGF1R, INSR, and IRS2, and promotes an insulin-sensitized state via up-regulation of  its target gene Lin28, 17/March/2018, 6.50 am

Introduction: What they say:   A study from the Stem Cell Transplantation Program, Division of Pediatric Hematology/Oncology, Boston Children’s Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts, USA shows that “The Lin28/let-7 axis […]
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