Ideas

July 9, 2018
Published by admin_auro at July 9, 2018
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Turning on the cancer-protecting angels in mutant p53-expressing human tumors: Emodin, isolated from Rhubarb and others,  increases the expression of tumor suppressors genes, such as CADM1, RECK, TA-p73, TAp63, p53, and others, induces regression of p53-mutated human tumors, via down regulation of its target gene, 9/July/2018, 11.51 am

From Significance of the study to Public health relevance:  Given that: (1) cancer suppressor p53 is mutated in more than 50% of human cancers of different […]
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July 9, 2018
Published by admin_auro at July 9, 2018
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Insulate your heart against cardiac dysfunction with flu vaccine: Influenza A (H1N1) vaccine-based adjunct therapy for cardiac hypertrophy and fibrosis: Influenza A (H1N1)/Flu vaccine decreases MiR-29 expression, activates wnt- signaling and its components GSK3B, ICAT/CTNNBIP1, HBP1 and GLIS2, attenuates pathologic hypertrophy, inhibits fibrosis of the heart tissue, and improves cardiac function via up regulation of its target gene, 9/July/2018, 11.41 am

Introduction: What they say:   A recent study from the Institute of Pharmacology and Toxicology, Technical University Munich (TUM), 80802, Munich, Germany; DZHK (German Center for Cardiovascular […]
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July 9, 2018
Published by admin_auro at July 9, 2018
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Safeguard your heart function with TB/BCG vaccine vaccine: TB/BCG vaccine based therapy for Cardiac repair and myocardial infarction: TB/BCG vaccine vaccine increases Agrin expression, activates Yap and ERK-mediated signaling,  replaces scar tissue with functional cardiomyocytes, and promotes cardiomyocyte regeneration and repair after myocardial infarction, via up regulation of its target gene, 9/July/2018, 10.17 am

Introduction: What they say: A recent study from Department of Molecular Cell Biology, Weizmann Institute of Science, Rehovot 76100, Israel; Department of Biomedical Engineering, Duke University, […]
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July 8, 2018
Published by admin_auro at July 8, 2018
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Vaccinate your heart against cardiac dysfunction: Influenza A (H1N1)-vaccine-based therapy for cardiomyocyte proliferation and heart regeneration: Influenza A (H1N1)-vaccine decreases tumor suppressor MiR-128 and cyclin-dependent kinase inhibitor p27 expression, increases SUZ12 expression, increases Cyclin E and CDK2 expression, promotes proliferation/re-entry of postnatal/adult cardiomyocytes, attenuates fibrosis, ameliorates cardiac dysfunction, and promotes heart repair in response to myocardial infarction, via up regulation of its target gene, 8/July/2018, 9.49  am

Introduction: What they say: A recent study from Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, 45267, USA; Key Laboratory […]
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