Ideas

July 12, 2018

Published by admin_auro at July 12, 2018

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CTB-UE vaccine-based therapy for autoimmune diabetes (TIDM): CTB-UE vaccine, known to eradicate infections caused by H. pylori, increases the expression of PD-L1, augments Tregs function, promotes immune tolerance, increases pancreatic β-cell proliferation and regeneration, increases insulin secretion, improves insulin sensitivity, increases energy utilization, and reverses TIDM, via up regulation of its target gene, 12/July/2018, 11.14 pm

Introduction: What they say A study from the International Center for T1D, Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, “L. Sacco” Department of Biomedical and Clinical […]

July 12, 2018

Published by admin_auro at July 12, 2018

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Inhibitors of heat shock response as longevity-promoters: 17-DMAG, a heat shock protein-90 (HSP-90) inhibitor, inhibits the expression of Ribosomal protein S6 kinase 1 (p70S6 Kinase) and extends mammalian life span via up regulation of its target gene, 12/July/2017, 1.20 pm

What they say? A study from the Institute of Healthy Ageing, Centre for Diabetes and Endocrinology, Department of Medicine, University College London, London WC1E 6JJ, UK shows that “Ribosomal […]

July 12, 2018

Published by admin_auro at July 12, 2018

Categories

Ideas
NAFLD

A flu vaccine-based therapy for lowering cholesterol, and triglycerides levels: Repurposing Influenza A/flu(H1N1) vaccine into a cholesterol-lowering vaccine that inhibits Non-alcoholic fatty liver disease (NAFLD): Influenza A/flu(H1N1) vaccine decreases the levels of HMGCR, triglycerides, free cholesterol, and total cholesterol and prevents the progression of Non-alcoholic fatty liver disease (NAFLD), via down regulation of its target gene, 12/July/2018, 1.04 pm

Significance of the study: Given that: (1) 15-30% of Western populations suffer from Non-alcoholic fatty liver disease (NAFLD), while 6-25% of Asian populations suffer from it; (2) 75 to […]

July 12, 2018

Published by admin_auro at July 12, 2018

Categories

A flavonoid way to lengthen lifespan: Quercetin, a flavonoid isolated from elder berries, onions and others, may increase insulin sensitivity, slow down cardiac aging, and increase life span, via up-regulation of BubR1 and others genes, 12/July/2018, 12.53 pm

What they say: Introduction: A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and […]