Ideas

Natural product-derived therapy for blood-stage Plasmodium infection: Fisetin, isolated from A. greggi , A. berlanderi, strawberry among others, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 19/January/2018, 10.41 am
Natural product-derived therapy for blood-stage Plasmodium infection: Fisetin, isolated from A. greggi , A. berlanderi, strawberry among others, decreases the expression of CTLA-4, PD-L1 and LAG-3, promotes CD4+ T-cell function, increases secretion of protective antibodies, promotes and clear blood-stage malaria via up regulation of its target gene, 19/January/2018, 10.41 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Department of Microbiology and Immunology, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA shows that “Regulatory T cells impede…

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Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF)  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/January/2017, 12.27 pm
Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF)  inhibits DNA methyltransferase 3a (Dnmt3a) expression, increases FGF21 expression, augments insulin sensitivity, increases glucose tolerance, and protects from diet-induced obesity and TIIDM, via up regulation of its target gene, 18/January/2017, 12.27 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from Nutritional Sciences and Toxicology Department, University of California, Berkeley, Berkeley, United States shows that “Dnmt3a is an epigenetic mediator of adipose insulin resistance.”…

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Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing 15-Deoxy-Delta-12,14-prostaglandin J2 (15d-PGJ2), Epicatechin and Matrine (15d-GJ2EM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 18/January/2018, 12.05 pm
Natural product-based therapy for Diabetic retinopathy: A pharmaceutical mixture encompassing 15-Deoxy-Delta-12,14-prostaglandin J2 (15d-PGJ2), Epicatechin and Matrine (15d-GJ2EM) inhibits Soluble epoxide hydrolase (sEH) expression, decreases toxic 19,20-dihydroxydocosapentaenoic acid levels, inhibits pericyte loss, vascular permeability, and inflammation of the eye and progression of diabetic retinopathy, via down regulation of its target gene, 18/January/2018, 12.05 pm 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Institute for Vascular Signalling, Centre for Molecular Medicine, Goethe University, Frankfurt am Main, Germany; and German Centre for Cardiovascular Research (DZHK) partner…

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Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF) decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 18/January/2017, 11.54 am
Vitamin-based therapy for body weight control, energy homeostasis and TIIDM: A pharmaceutical mixture (PMSF) encompassing Pyridoxamine (PM) and Sildenafil (SF) decreases CADM1 and its downstream target genes that promote glucose-induced insulin secretion, improves insulin sensitivity, increases energy utilization, promotes weight loss and protects from diet-induced obesity and TIIDM via up regulation of its target gene, 18/January/2017, 11.54 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A study from the Max Delbrück Center for Molecular Medicine, Berlin, Germany shows that “Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule1.”…

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Lifespan extension therapy:  Sildenafil (brand name: Viagra, Revatio and others), used in the treatment of erectile dysfunction and pulmonary arterial hypertension, increases life span via up-regulation of its target gene BubR1, 18/January/2018, 11.46 am
Lifespan extension therapy:  Sildenafil (brand name: Viagra, Revatio and others), used in the treatment of erectile dysfunction and pulmonary arterial hypertension, increases life span via up-regulation of its target gene BubR1, 18/January/2018, 11.46 am 960 720 Dr Boomi's Genom-2-Discovery Center

 What they say: Introduction:  A recent study from the Department of Genetics, Paul F. Glenn Laboratories for the Biological Mechanisms of Aging Harvard Medical School, Boston,USA; and Department of Pharmacology, School…

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Vitamin-based therapy for Stroke: Vitamin-D/Cholecalciferol attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 18/January/2018, 11.34 am
Vitamin-based therapy for Stroke: Vitamin-D/Cholecalciferol attenuates hippocampal neurons injury, augments regenerative neurogenesis after Ischemic Stroke, and ameliorates stroke damage and neurological deficits via up regulation of its target genes BDNF and NAMPT, 18/January/2018, 11.34 am 960 720 Dr Boomi's Genom-2-Discovery Center

Introduction: What they say A recent study from Research Center for Neurobiology and Department of Neurobiology, Xuzhou Medical College, 209 Tongshan Road, Xuzhou, Jiangsu 221004, PR China; and School of Public…

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